Literature DB >> 3013004

Chromosomal assignment of the genes for human aldehyde dehydrogenase-1 and aldehyde dehydrogenase-2.

L C Hsu, A Yoshida, T Mohandas.   

Abstract

Chromosomal assignment of the genes for two major human aldehyde dehydrogenase isozymes, that is, cytosolic aldehyde dehydrogenase-1 (ALDH1) and mitochondrial aldehyde dehydrogenase-2 (ALDH2) were determined. Genomic DNA, isolated from a panel of mouse-human and Chinese hamster-human hybrid cell lines, was digested by restriction endonucleases and subjected to Southern blot hybridization using cDNA probes for ALDH1 and for ALDH2. Based on the distribution pattern of ALDH1 and ALDH2 in cell hybrids, ALDH1 was assigned to the long arm of human chromosome 9 and ALDH2 to chromosome 12.

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Year:  1986        PMID： 3013004      PMCID： PMC1684817     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  19 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Subcellular localization of the F1 and F2 isozymes of horse liver aldehyde dehydrogenase.

Authors:  J H Eckfeldt; T Yonetani
Journal:  Arch Biochem Biophys       Date:  1976-08       Impact factor: 4.013

3.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

4.  Racial differences in alcohol sensitivity: a new hypothesis.

Authors:  H W Goedde; S Harada; D P Agarwal
Journal:  Hum Genet       Date:  1979-10-02       Impact factor: 4.132

5.  Isolation and characterization of aldehyde dehydrogenase isozymes from usual and atypical human livers.

Authors:  M Ikawa; C C Impraim; G Wang; A Yoshida
Journal:  J Biol Chem       Date:  1983-05-25       Impact factor: 5.157

6.  Localization of bovine liver aldehyde dehydrogenase isozymes and their immunological properties.

Authors:  N Kitabatake; R Sasaki; H Chiba
Journal:  J Biochem       Date:  1981-04       Impact factor: 3.387

7.  Mouse aldehyde dehydrogenase genetics: positioning of Ahd-1 on chromosome 4.

Authors:  R S Holmes; G P Timms
Journal:  Anim Blood Groups Biochem Genet       Date:  1981

8.  Regional localization of human gene loci on chromosome 9: studies of somatic cell hybrids containing human translocations.

Authors:  T Mohandas; R S Sparkes; M C Sparkes; J D Shulkin; K E Toomey; S J Funderburk
Journal:  Am J Hum Genet       Date:  1979-09       Impact factor: 11.025

9.  Genetics of aldehyde dehydrogenase isozymes in the mouse: evidence for multiple loci and localization of Ahd-2 on chromosome 19.

Authors:  G P Timms; R S Holmes
Journal:  Genetics       Date:  1981-02       Impact factor: 4.562

10.  Human liver aldehyde dehydrogenase in Chinese and Asiatic Indians: gene deletion and its possible implications in alcohol metabolism.

Authors:  Y S Teng
Journal:  Biochem Genet       Date:  1981-02       Impact factor: 1.890
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  15 in total

1.  Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism.

Authors:  C C Chen; R B Lu; Y C Chen; M F Wang; Y C Chang; T K Li; S J Yin
Journal:  Am J Hum Genet       Date:  1999-09       Impact factor: 11.025

Review 2.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  Genetic predisposition to alcoholic liver disease.

Authors:  C P Day; M F Bassendine
Journal:  Gut       Date:  1992-11       Impact factor: 23.059

Review 4.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

5.  Comparison of human ZFY and ZFX transcripts.

Authors:  M S Palmer; P Berta; A H Sinclair; B Pym; P N Goodfellow
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

6.  Effects of genetic polymorphisms in alcohol-metabolizing enzymes on alcohol hypersensitivity and alcohol-related health problems in orientals.

Authors:  T Takeshita; K Morimoto
Journal:  Environ Health Prev Med       Date:  1996-04       Impact factor: 3.674

7.  Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant.

Authors:  D W Crabb; H J Edenberg; W F Bosron; T K Li
Journal:  J Clin Invest       Date:  1989-01       Impact factor: 14.808

8.  Restriction fragment length polymorphism of human aldehyde dehydrogenase 1 and aldehyde dehydrogenase 2 loci.

Authors:  A Yoshida; S H Chen
Journal:  Hum Genet       Date:  1989-09       Impact factor: 4.132

9.  A 530kb YAC contig tightly linked to the Friedreich ataxia locus contains five CpG clusters and a new highly polymorphic microsatellite.

Authors:  R Fujita; G Sirugo; F Duclos; H Abderrahim; D Le Paslier; D Cohen; B H Brownstein; D Schlessinger; J L Mandel; M Koenig
Journal:  Hum Genet       Date:  1992-07       Impact factor: 4.132

10.  Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDH1A1*4.

Authors:  Shelley M Moore; Tiebing Liang; Tamara J Graves; Kevin M McCall; Lucinda G Carr; Cindy L Ehlers
Journal:  Hum Genomics       Date:  2009-07       Impact factor: 4.639
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