Literature DB >> 3009882

Localization of temperature-sensitive transformation mutations and back mutations in the Rous sarcoma virus src gene.

V J Fincham, J A Wyke.   

Abstract

Cloning and sequencing of two temperature-sensitive transforming mutations of Rous sarcoma virus reveal that their lesions are due to distinct but close single amino acid changes near the carboxy terminus of the v-src gene product. Back mutations to wild type result from second mutations at either nearby or distant sites.

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Year:  1986        PMID： 3009882      PMCID： PMC252966     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  34 in total

1.  Reversion of temperature sensitive transformation mutants of Rous sarcoma virus and its effect on the expression of tumour specific surface antigen.

Authors:  J A Wyke; R Kurth
Journal:  J Gen Virol       Date:  1978-09       Impact factor: 3.891

2.  Dissociation of transformation parameters using temperature-conditional mutants of Rous sarcoma virus.

Authors:  M J Weber; R R Friis
Journal:  Cell       Date:  1979-01       Impact factor: 41.582

3.  Genetic recombination among temperature-sensitive mutnats of Rous sarcoma virus.

Authors:  J A Wyke; J G Bell; J A Beamand
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1975

4.  Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus.

Authors:  D Becker; R Kurth; D Critchley; R Friis; H Bauer
Journal:  J Virol       Date:  1977-03       Impact factor: 5.103

5.  N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene.

Authors:  F R Cross; E A Garber; H Hanafusa
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

6.  Complementation of transforming functions by temperature-sensitive mutants of avian sarcoma virus.

Authors:  J A Wyke
Journal:  Virology       Date:  1973-07       Impact factor: 3.616

7.  The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant.

Authors:  S Kawai; H Hanafusa
Journal:  Virology       Date:  1971-11       Impact factor: 3.616

8.  The selective isolation of temperature-sensitive mutants of Rous sarcoma virus.

Authors:  J A Wyke
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

9.  Site-directed mutagenesis of the src gene of Rous sarcoma virus: construction and characterization of a deletion mutant temperature sensitive for transformation.

Authors:  D Bryant; J T Parsons
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  14 in total

1.  Development of avian sarcoma and leukosis virus-based vector-packaging cell lines.

Authors:  A W Stoker; M J Bissell
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

2.  Interallelic complementation among DER/flb alleles: implications for the mechanism of signal transduction by receptor-tyrosine kinases.

Authors:  E Raz; E D Schejter; B Z Shilo
Journal:  Genetics       Date:  1991-09       Impact factor: 4.562

3.  Creation and characterization of temperature-sensitive mutants of the lck tyrosine protein kinase.

Authors:  T R Hurley; K E Amrein; B M Sefton
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

4.  Inhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src.

Authors:  D J McCarley; J T Parsons; D C Benjamin; S J Parsons
Journal:  J Virol       Date:  1987-06       Impact factor: 5.103

5.  Sequence and functional differences between Schmidt-Ruppin D and Schmidt-Ruppin A strains of pp60v-src.

Authors:  S Reddy; D Mazzu; D Mahan; D Shalloway
Journal:  J Virol       Date:  1990-07       Impact factor: 5.103

6.  Sequence variation of the Rous sarcoma virus PrA src gene.

Authors:  Z J Liu; P B Hackett
Journal:  Nucleic Acids Res       Date:  1989-05-25       Impact factor: 16.971

7.  Isolation of temperature-sensitive Abelson virus mutants by site-directed mutagenesis.

Authors:  A Engelman; N Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

8.  A single point mutation has pleiotropic effects on pp60v-src function.

Authors:  M J Welham; J A Wyke
Journal:  J Virol       Date:  1988-06       Impact factor: 5.103

9.  Mutations in v-Src SH3 and catalytic domains that jointly confer temperature-sensitive transformation with minimal temperature-dependent changes in cellular tyrosine phosphorylation.

Authors:  A D Catling; V J Fincham; M C Frame; B Haefner; J A Wyke
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103

10.  Ala-->Gly mutation in the putative catalytic loop confers temperature sensitivity on Ros, insulin receptor, and insulin-like growth factor I receptor protein-tyrosine kinases.

Authors:  J Chen; T Hanafusa; L H Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205
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