Literature DB >> 2161957

Sequence and functional differences between Schmidt-Ruppin D and Schmidt-Ruppin A strains of pp60v-src.

S Reddy1, D Mazzu, D Mahan, D Shalloway.   

Abstract

We show that Schmidt-Ruppin D pp60v-src kinase activity is reduced by a mutation previously shown to be associated with Schmidt-Ruppin A pp60v-src temperature sensitivity and that its reduced transforming activity is associated with a conformational change in the SH3 region. The evolutionary relationship of seven v-src strains was studied by using parsimony analysis.

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Year:  1990        PMID: 2161957      PMCID: PMC249629          DOI: 10.1128/JVI.64.7.3545-3550.1990

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  33 in total

1.  The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.

Authors:  C A Koch; M Moran; I Sadowski; T Pawson
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

2.  Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.

Authors:  H Hirai; H E Varmus
Journal:  Mol Cell Biol       Date:  1990-04       Impact factor: 4.272

3.  Features of the pp60v-src carboxyl terminus that are required for transformation.

Authors:  P Yaciuk; D Shalloway
Journal:  Mol Cell Biol       Date:  1986-08       Impact factor: 4.272

4.  v-src mutations outside the carboxyl-coding region are not sufficient to fully activate transformation by pp60c-src in NIH 3T3 cells.

Authors:  S Reddy; P Yaciuk; T E Kmiecik; P M Coussens; D Shalloway
Journal:  Mol Cell Biol       Date:  1988-02       Impact factor: 4.272

Review 5.  Genetics of src: structure and functional organization of a protein tyrosine kinase.

Authors:  J T Parsons; M J Weber
Journal:  Curr Top Microbiol Immunol       Date:  1989       Impact factor: 4.291

Review 6.  Cell transformation by the viral src oncogene.

Authors:  R Jove; H Hanafusa
Journal:  Annu Rev Cell Biol       Date:  1987

7.  A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner.

Authors:  M F Verderame; J M Kaplan; H E Varmus
Journal:  J Virol       Date:  1989-01       Impact factor: 5.103

Review 8.  The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.

Authors:  S K Hanks; A M Quinn; T Hunter
Journal:  Science       Date:  1988-07-01       Impact factor: 47.728

Review 9.  Avian sarcoma viruses.

Authors:  L H Wang; H Hanafusa
Journal:  Virus Res       Date:  1988-02       Impact factor: 3.303

10.  Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein.

Authors:  J Y Kato; T Takeya; C Grandori; H Iba; J B Levy; H Hanafusa
Journal:  Mol Cell Biol       Date:  1986-12       Impact factor: 4.272

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  4 in total

1.  Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src.

Authors:  R R Roussel; S R Brodeur; D Shalloway; A P Laudano
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

2.  Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90.

Authors:  Edgar E Boczek; Lasse G Reefschläger; Marco Dehling; Tobias J Struller; Elisabeth Häusler; Andreas Seidl; Ville R I Kaila; Johannes Buchner
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-08       Impact factor: 11.205

3.  Role of Src signal transduction pathways in scatter factor-mediated cellular protection.

Authors:  Saijun Fan; Qinghui Meng; John J Laterra; Eliot M Rosen
Journal:  J Biol Chem       Date:  2008-12-01       Impact factor: 5.157

Review 4.  Regulatory Roles of the N-Terminal Intrinsically Disordered Region of Modular Src.

Authors:  Goro Kato
Journal:  Int J Mol Sci       Date:  2022-02-17       Impact factor: 5.923

  4 in total

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