Depressive symptoms and error-related brain activity in CPS-referred children.

Early adversity such as maltreatment is associated with increased risk for psychopathology and atypical neurological development in children. The present study examined associations between depressive symptoms and error-related brain activity (the error-related negativity, or ERN) among children involved with Child Protective Services (CPS) and among comparison children. Results indicate that the relation between depressive symptoms and ERN amplitude depends on CPS involvement, such that depressive symptoms were associated with blunted ERNs only for CPS-referred children. The present study can inform future research investigating the mechanisms by which experiences of adversity affect the association between symptoms and error-related brain activity.