Literature DB >> 30093447

Ultrahigh Dose-rate Radiotherapy: Next Steps for FLASH-RT.

Kevin J Harrington1.   

Abstract

A new way of delivering radiotherapy at very high dose rates is described and compared with conventional radiotherapy. The ultrahigh dose-rate therapy reduces damage to normal pig skin and exerts potent activity against spontaneous nasal tumors in cat patients. The implications for clinical development of this approach are discussed.See related article by Vozenin et al., p. 35. ©2018 American Association for Cancer Research.

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Mesh：

Year:  2018        PMID： 30093447     DOI： 10.1158/1078-0432.CCR-18-1796

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  17 in total

Review 1.  Proton RBE dependence on dose in the setting of hypofractionation.

Authors:  Thomas Friedrich
Journal:  Br J Radiol       Date:  2019-08-28       Impact factor: 3.039

2.  Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System.

Authors:  Eric S Diffenderfer; Ioannis I Verginadis; Michele M Kim; Khayrullo Shoniyozov; Anastasia Velalopoulou; Denisa Goia; Mary Putt; Sarah Hagan; Stephen Avery; Kevin Teo; Wei Zou; Alexander Lin; Samuel Swisher-McClure; Cameron Koch; Ann R Kennedy; Andy Minn; Amit Maity; Theresa M Busch; Lei Dong; Costas Koumenis; James Metz; Keith A Cengel
Journal:  Int J Radiat Oncol Biol Phys       Date:  2020-02-01       Impact factor: 7.038

Review 3.  Biological Benefits of Ultra-high Dose Rate FLASH Radiotherapy: Sleeping Beauty Awoken.

Authors:  M-C Vozenin; J H Hendry; C L Limoli
Journal:  Clin Oncol (R Coll Radiol)       Date:  2019-04-19       Impact factor: 4.126

Review 4.  Ultra-high dose rate electron beams and the FLASH effect: From preclinical evidence to a new radiotherapy paradigm.

Authors:  Emil Schüler; Munjal Acharya; Pierre Montay-Gruel; Billy W Loo; Marie-Catherine Vozenin; Peter G Maxim
Journal:  Med Phys       Date:  2022-01-19       Impact factor: 4.506

5.  Ultra-High-Dose-Rate FLASH Irradiation Limits Reactive Gliosis in the Brain.

Authors:  Pierre Montay-Gruel; Mineh Markarian; Barrett D Allen; Jabra D Baddour; Erich Giedzinski; Patrik Goncalves Jorge; Benoît Petit; Claude Bailat; Marie-Catherine Vozenin; Charles Limoli; Munjal M Acharya
Journal:  Radiat Res       Date:  2020-12-01       Impact factor: 2.841

6.  An open invitation to join the Pediatric Proton/Photon Consortium Registry to standardize data collection in pediatric radiation oncology.

Authors:  Miranda P Lawell; Daniel J Indelicato; Arnold C Paulino; William Hartsell; Nadia N Laack; Ralph P Ermoian; John P Perentesis; Ralph Vatner; Stephanie Perkins; Victor S Mangona; Christine E Hill-Kayser; Suzanne L Wolden; Young Kwok; John Han-Chih Chang; J Ben Wilkinson; Iain MacEwan; Andrew L Chang; Bree R Eaton; Matthew M Ladra; Sara L Gallotto; Elizabeth A Weyman; Benjamin V M Bajaj; Sujith Baliga; Beow Y Yeap; Amy Berrington de Gonzalez; Torunn I Yock
Journal:  Br J Radiol       Date:  2019-11-01       Impact factor: 3.039

7.  Hypofractionated FLASH-RT as an Effective Treatment against Glioblastoma that Reduces Neurocognitive Side Effects in Mice.

Authors:  Pierre Montay-Gruel; Munjal M Acharya; Charles L Limoli; Marie-Catherine Vozenin; Patrik Gonçalves Jorge; Benoît Petit; Ioannis G Petridis; Philippe Fuchs; Ron Leavitt; Kristoffer Petersson; Maude Gondré; Jonathan Ollivier; Raphael Moeckli; François Bochud; Claude Bailat; Jean Bourhis; Jean-François Germond
Journal:  Clin Cancer Res       Date:  2020-10-15       Impact factor: 13.801

8.  Neuroprotection of Radiosensitive Juvenile Mice by Ultra-High Dose Rate FLASH Irradiation.

Authors:  Yasaman Alaghband; Samantha N Cheeks; Barrett D Allen; Pierre Montay-Gruel; Ngoc-Lien Doan; Benoit Petit; Patrik Goncalves Jorge; Erich Giedzinski; Munjal M Acharya; Marie-Catherine Vozenin; Charles L Limoli
Journal:  Cancers (Basel)       Date:  2020-06-24       Impact factor: 6.639

Review 9.  FLASH and minibeams in radiation therapy: the effect of microstructures on time and space and their potential application to protontherapy.

Authors:  Alejandro Mazal; Yolanda Prezado; Carme Ares; Ludovic de Marzi; Annalisa Patriarca; Raymond Miralbell; Vincent Favaudon
Journal:  Br J Radiol       Date:  2020-02-12       Impact factor: 3.039

10.  Establishment and Initial Experience of Clinical FLASH Radiotherapy in Canine Cancer Patients.

Authors:  Elise Konradsson; Maja L Arendt; Kristine Bastholm Jensen; Betina Børresen; Anders E Hansen; Sven Bäck; Annemarie T Kristensen; Per Munck Af Rosenschöld; Crister Ceberg; Kristoffer Petersson
Journal:  Front Oncol       Date:  2021-05-13       Impact factor: 6.244
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