Literature DB >> 30070834

Abyssomicin Monomers and Dimers from the Marine-Derived Streptomyces koyangensis SCSIO 5802.

Hongbo Huang1, Yongxiang Song1, Xin Li2, Xin Wang2, Chunyao Ling1, Xiangjing Qin1, Zhenbin Zhou1, Qinglian Li1, Xiaoyi Wei3, Jianhua Ju1.   

Abstract

Three new abyssomicin monomers designated neoabyssomicins D (1), E (2), and A2 (3) and the two dimeric neoabyssomicins F (4) and G (5) were discovered from the marine-derived Streptomyces koyangensis SCSIO 5802, and their structures rigorously elucidated. Neoabyssomicin D (1) possesses an unprecedented 8/5/5/7 ring skeleton, the biosynthesis of which (as well as 2) is proposed herein. Additionally, dimeric agents 4 and 5 were found to be active against methicillin-resistant Staphylococcus aureus and vesicular stomatitis virus, respectively.

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Year:  2018        PMID： 30070834     DOI： 10.1021/acs.jnatprod.8b00448

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Cytotoxic and antimicrobial activities of secondary metabolites isolated from the deep-sea-derived Actinoalloteichus cyanogriseus 12A22.

Authors:  Xiaoying Zhang; Chunfeng Song; Yan Bai; Jiangchun Hu; Huaqi Pan
Journal:  3 Biotech       Date:  2021-05-21       Impact factor: 2.893

Review 2.  Bioactive Compounds Isolated from Marine-Derived Microbes in China: 2009-2018.

Authors:  Weiwei Sun; Wenhui Wu; Xueling Liu; Diana A Zaleta-Pinet; Benjamin R Clark
Journal:  Mar Drugs       Date:  2019-06-06       Impact factor: 5.118

3.  Out of the Abyss: Genome and Metagenome Mining Reveals Unexpected Environmental Distribution of Abyssomicins.

Authors:  Alba Iglesias; Adriel Latorre-Pérez; James E M Stach; Manuel Porcar; Javier Pascual
Journal:  Front Microbiol       Date:  2020-04-15       Impact factor: 5.640

Review 4.  Recent progresses in marine microbial-derived antiviral natural products.

Authors:  Yun-Fei Teng; Li Xu; Mei-Yan Wei; Chang-Yun Wang; Yu-Cheng Gu; Chang-Lun Shao
Journal:  Arch Pharm Res       Date:  2020-11-21       Impact factor: 4.946

5.  Genome Mining and Metabolic Profiling Uncover Polycyclic Tetramate Macrolactams from Streptomyces koyangensis SCSIO 5802.

Authors:  Wenjuan Ding; Jiajia Tu; Huaran Zhang; Xiaoyi Wei; Jianhua Ju; Qinglian Li
Journal:  Mar Drugs       Date:  2021-07-31       Impact factor: 5.118

Review 6.  Marine Bacterial Secondary Metabolites: A Treasure House for Structurally Unique and Effective Antimicrobial Compounds.

Authors:  Ramanathan Srinivasan; Arunachalam Kannappan; Chunlei Shi; Xiangmin Lin
Journal:  Mar Drugs       Date:  2021-09-23       Impact factor: 5.118

Review 7.  Marine Actinobacteria a New Source of Antibacterial Metabolites to Treat Acne Vulgaris Disease-A Systematic Literature Review.

Authors:  Maria Clara De La Hoz-Romo; Luis Díaz; Luisa Villamil
Journal:  Antibiotics (Basel)       Date:  2022-07-18

8.  The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway.

Authors:  Jonathan A Clinger; Xiachang Wang; Wenlong Cai; Yanyan Zhu; Mitchell D Miller; Chang-Guo Zhan; Steven G Van Lanen; Jon S Thorson; George N Phillips
Journal:  Proteins       Date:  2020-10-21

Review 9.  From Ocean to Medicine: Pharmaceutical Applications of Metabolites from Marine Bacteria.

Authors:  José Diogo Santos; Inês Vitorino; Fernando Reyes; Francisca Vicente; Olga Maria Lage
Journal:  Antibiotics (Basel)       Date:  2020-07-28

10.  Atypical Spirotetronate Polyketides Identified in the Underexplored Genus Streptacidiphilus.

Authors:  Somayah S Elsayed; Grégory Genta-Jouve; Víctor J Carrión; Peter H Nibbering; Maxime A Siegler; Wietse de Boer; Thomas Hankemeier; Gilles P van Wezel
Journal:  J Org Chem       Date:  2020-07-31       Impact factor: 4.354
  10 in total

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