Literature DB >> 30061264

Controlling Nutritional Status (CONUT) Score Is a Prognostic Marker in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy.

Nobuya Daitoku1, Yuji Miyamoto1, Ryuma Tokunaga1, Yuki Sakamoto1, Yukiharu Hiyoshi1, Masaaki Iwatsuki1, Yoshifumi Baba1, Shiro Iwagami1, Naoya Yoshida1, Hideo Baba2.   

Abstract

BACKGROUND/AIM: The Controlling Nutritional Status (CONUT) score is a useful nutritional evaluation, that is calculated from serum albumin, total cholesterol concentrations, and total lymphocyte count. This study aimed to investigate the association between the CONUT score and prognosis in patients with metastatic colorectal cancer (mCRC). PATIENTS AND METHODS: The CONUT score was retrospectively calculated in 211 patients with mCRC receiving first-line chemotherapy. The patients were divided into three groups: the CONUT low-group (0-1), intermediate-group (2-4), and high-group (5-). The associations of the CONUT score with clinicopathological factors and survival outcomes were evaluated.
RESULTS: The higher CONUT score was significantly associated with synchronous metastases, and no primary tumor resection. The higher CONUT score group showed a significant shorter progression-free survival (log-rank p<0.05) and overall survival (log-rank p<0.001).
CONCLUSION: The CONUT score is a useful prognostic marker for predicting survival outcomes of patients with mCRC. Copyright
© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  CONUT score; colorectal cancer; metastasis; prognostic marker

Mesh：

Substances：

Year:  2018        PMID： 30061264     DOI： 10.21873/anticanres.12802

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  10 in total

1.  The Controlling Nutritional Status (CONUT) Score as a prognostic factor for obstructive colorectal cancer patients received stenting as a bridge to curative surgery.

Authors:  Ryuichiro Sato; Masaya Oikawa; Tetsuya Kakita; Takaho Okada; Tomoya Abe; Takashi Yazawa; Haruyuki Tsuchiya; Naoya Akazawa; Masaki Sato; Tetsuya Ohira; Yoshihiro Harada; Haruka Okano; Kei Ito; Takashi Tsuchiya
Journal:  Surg Today       Date:  2020-07-04       Impact factor: 2.549

2.  Prognostic Value of Combined Tumor Marker and Controlling Nutritional Status (CONUT) Score in Colorectal Cancer Patients.

Authors:  Manabu Yamamoto; Hiroaki Saito; Chihiro Uejima; Akimitsu Tanio; Yoichiro Tada; Tomoyuki Matsunaga; Teruhisa Sakamoto; Soichiro Honjo; Keigo Ashida; Yoshiyuki Fujiwara
Journal:  Yonago Acta Med       Date:  2019-03-28       Impact factor: 1.641

3.  Combined Features Based on Preoperative Controlling Nutritional Status Score and Circulating Tumour Cell Status Predict Prognosis for Colorectal Cancer Patients Treated with Curative Resection.

Authors:  Chaogang Yang; Chen Wei; Shuyi Wang; Song Han; Dongdong Shi; Chunxiao Zhang; Xiaobin Lin; Rongzhang Dou; Bin Xiong
Journal:  Int J Biol Sci       Date:  2019-05-12       Impact factor: 6.580

4.  Dose Intensity/Body Surface Area Ratio is a Novel Marker Useful for Predicting Response to Lenvatinib against Hepatocellular Carcinoma.

Authors:  Yuji Eso; Shigeharu Nakano; Masako Mishima; Soichi Arasawa; Eriko Iguchi; Fumiyasu Nakamura; Haruhiko Takeda; Atsushi Takai; Ken Takahashi; Kojiro Taura; Hiroshi Seno
Journal:  Cancers (Basel)       Date:  2019-12-22       Impact factor: 6.639

5.  High Preoperative Controlling Nutritional Status Score Predicts a Poor Prognosis in Patients with Localized Upper Tract Urothelial Cancer: A Propensity Score Matching Study in a Large Chinese Center.

Authors:  Zhengqing Bao; Yifan Li; Bao Guan; Gengyan Xiong; Lei Zhang; Qi Tang; Tianyu Wang; Xuesong Li; Dong Fang; Liqun Zhou
Journal:  Cancer Manag Res       Date:  2020-01-15       Impact factor: 3.989

6.  Activin A promotes cell proliferation, invasion and migration and predicts poor prognosis in patients with colorectal cancer.

Authors:  Nobuya Daitoku; Yuji Miyamoto; Yukiharu Hiyoshi; Ryuma Tokunaga; Yuki Sakamoto; Hiroshi Sawayama; Takatsugu Ishimoto; Yoshifumi Baba; Naoya Yoshida; Hideo Baba
Journal:  Oncol Rep       Date:  2022-04-21       Impact factor: 3.906

7.  Preoperative skeletal muscle status is associated with tumor-infiltrating lymphocytes and prognosis in patients with colorectal cancer.

Authors:  Nobuya Daitoku; Yuji Miyamoto; Yukiharu Hiyoshi; Ryuma Tokunaga; Yuki Sakamoto; Hiroshi Sawayama; Takatsugu Ishimoto; Yoshifumi Baba; Naoya Yoshida; Hideo Baba
Journal:  Ann Gastroenterol Surg       Date:  2022-03-25

8.  Prognostic impact of the Controlling Nutritional Status score in patients with non-small cell lung cancer treated with pembrolizumab.

Authors:  Taro Ohba; Shinkichi Takamori; Ryo Toyozawa; Kaname Nosaki; Yasuhiro Umeyama; Naoki Haratake; Naoko Miura; Masafumi Yamaguchi; Kenichi Taguchi; Takashi Seto; Mototsugu Shimokawa; Mitsuhiro Takenoyama
Journal:  J Thorac Dis       Date:  2019-09       Impact factor: 2.895

9.  Controlling Nutritional Status (CONUT) Score is Associated with Overall Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib: A Multicenter Cohort Study.

Authors:  Shigeo Shimose; Takumi Kawaguchi; Hideki Iwamoto; Masatoshi Tanaka; Ken Miyazaki; Miki Ono; Takashi Niizeki; Tomotake Shirono; Shusuke Okamura; Masahito Nakano; Hideya Suga; Taizo Yamaguchi; Yoshinori Yokokura; Kazunori Noguchi; Hironori Koga; Takuji Torimura
Journal:  Nutrients       Date:  2020-04-13       Impact factor: 5.717

10.  Nutritional and inflammatory measures predict survival of patients with stage IV colorectal cancer.

Authors:  Yasuyuki Takamizawa; Dai Shida; Narikazu Boku; Yuya Nakamura; Yuka Ahiko; Takefumi Yoshida; Taro Tanabe; Atsuo Takashima; Yukihide Kanemitsu
Journal:  BMC Cancer       Date:  2020-11-11       Impact factor: 4.430
  10 in total

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