Literature DB >> 30050770

Blood based biomarkers beyond genomics for lung cancer screening.

Samir M Hanash1, Edwin Justin Ostrin2, Johannes F Fahrmann1.   

Abstract

While there is considerable interest at the present time in the development of so-called liquid biopsy approaches for cancer detection based notably on circulating tumor DNA, there are other types of potential biomarkers that show promise for lung cancer screening and early detection. Here we review approaches and some of the promising markers based on proteomics, metabolomics and the immune response to tumor antigens in the form of autoantibodies.

Entities:  

Keywords:  Biomarkers; autoantibodies; metabolites; proteins

Year:  2018        PMID： 30050770      PMCID： PMC6037962          DOI： 10.21037/tlcr.2018.05.13

Source DB:  PubMed          Journal:  Transl Lung Cancer Res        ISSN： 2218-6751


  84 in total

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4.  Probability of cancer in high-risk patients predicted by the protein-based lung cancer biomarker panel in China: LCBP study.

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5.  Comparative Study of Autoantibody Responses between Lung Adenocarcinoma and Benign Pulmonary Nodules.

Authors:  Jie Wang; Shilpa Shivakumar; Kristi Barker; Yanyang Tang; Garrick Wallstrom; Jin G Park; Jun-Chieh J Tsay; Harvey I Pass; William N Rom; Joshua LaBaer; Ji Qiu
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Authors:  William R Wikoff; Samir Hanash; Brian DeFelice; Suzanne Miyamoto; Matt Barnett; Yang Zhao; Gary Goodman; Ziding Feng; David Gandara; Oliver Fiehn; Ayumu Taguchi
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8.  Results from the European Prospective Investigation into Cancer and Nutrition Link Vitamin B6 Catabolism and Lung Cancer Risk.

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Journal:  Cancer Res       Date:  2017-10-25       Impact factor: 12.701

9.  Establishment of a multi-analyte serum biomarker panel to identify lymph node metastases in non-small cell lung cancer.

Authors:  Jeffrey A Borgia; Sanjib Basu; L Penfield Faber; Anthony W Kim; John S Coon; Kelly A Kaiser-Walters; Cristina Fhied; Sherene Thomas; Omid Rouhi; William H Warren; Philip Bonomi; Michael J Liptay
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10.  Clinical validation of an autoantibody test for lung cancer.

Authors:  P Boyle; C J Chapman; S Holdenrieder; A Murray; C Robertson; W C Wood; P Maddison; G Healey; G H Fairley; A C Barnes; J F R Robertson
Journal:  Ann Oncol       Date:  2010-07-30       Impact factor: 32.976
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  15 in total

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2.  Identification of Serum miRNA-423-5p Expression Signature in Somatotroph Adenomas.

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3.  Discovery of a putative blood-based protein signature associated with response to ALK tyrosine kinase inhibition.

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Review 5.  Blood-based Biomarkers for Early Diagnosis of Lung Cancer: A Review Article.

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6.  Cyclic Peptide Mimotopes for the Detection of Serum Anti-ATIC Autoantibody Biomarker in Hepato-Cellular Carcinoma.

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7.  LC-MS/MS-Based Quantitative Proteomics Analysis of Different Stages of Non-Small-Cell Lung Cancer.

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8.  Aberrant lactate dehydrogenase A signaling contributes metabolic signatures in pancreatic cancer.

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9.  Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach.

Authors:  Andrzej Ciereszko; Mariola A Dietrich; Mariola Słowińska; Joanna Nynca; Michał Ciborowski; Joanna Kisluk; Anna Michalska-Falkowska; Joanna Reszec; Ewa Sierko; Jacek Nikliński
Journal:  PLoS One       Date:  2019-10-17       Impact factor: 3.240

10.  Validation of Lung EpiCheck, a novel methylation-based blood assay, for the detection of lung cancer in European and Chinese high-risk individuals.

Authors:  Mina Gaga; Joanna Chorostowska-Wynimko; Ildikó Horváth; Martin C Tammemagi; David Shitrit; Vered H Eisenberg; Hao Liang; David Stav; Dan Levy Faber; Maarten Jansen; Yael Raviv; Vasileios Panagoulias; Piotr Rudzinski; Gabriel Izbicki; Ohad Ronen; Adiv Goldhaber; Rawia Moalem; Nadir Arber; Ilana Haas; Qinghua Zhou
Journal:  Eur Respir J       Date:  2021-01-14       Impact factor: 16.671
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