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Literature DB >> 3003687

The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene.

T I Bonner, H Oppermann, P Seeburg, S B Kerby, M A Gunnell, A C Young, U R Rapp.

Abstract

The complete 648 amino acid sequence of the human raf oncogene was deduced from the 2977 nucleotide sequence of a fetal liver cDNA. The cDNA has been used to obtain clones which extend the human c-raf-1 locus by an additional 18.9 kb at the 5' end and contain all the remaining coding exons.

Entities: Gene Species

Mesh：

Substances：

Year: 1986 PMID： 3003687 PMCID： PMC339479 DOI： 10.1093/nar/14.2.1009

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

19 in total

1. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1.

Authors: C J Sherr; C W Rettenmier; R Sacca; M F Roussel; A T Look; E R Stanley
Journal: Cell Date: 1985-07 Impact factor: 41.582

2. 3' non-coding region sequences in eukaryotic messenger RNA.

Authors: N J Proudfoot; G G Brownlee
Journal: Nature Date: 1976-09-16 Impact factor: 49.962

3. A catalogue of splice junction sequences.

Authors: S M Mount
Journal: Nucleic Acids Res Date: 1982-01-22 Impact factor: 16.971

4. A simple method for displaying the hydropathic character of a protein.

Authors: J Kyte; R F Doolittle
Journal: J Mol Biol Date: 1982-05-05 Impact factor: 5.469

5. The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

Authors: R M Lawn; E F Fritsch; R C Parker; G Blake; T Maniatis
Journal: Cell Date: 1978-12 Impact factor: 41.582

6. Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins.

Authors: K Moelling; B Heimann; P Beimling; U R Rapp; T Sander
Journal: Nature Date: 1984 Dec 6-12 Impact factor: 49.962

7. Molecular cloning of an activated human oncogene, homologous to v-raf, from primary stomach cancer.

Authors: K Shimizu; Y Nakatsu; M Sekiguchi; K Hokamura; K Tanaka; M Terada; T Sugimura
Journal: Proc Natl Acad Sci U S A Date: 1985-09 Impact factor: 11.205

8. Ubiquitous, interspersed repeated sequences in mammalian genomes.

Authors: W R Jelinek; T P Toomey; L Leinwand; C H Duncan; P A Biro; P V Choudary; S M Weissman; C M Rubin; C M Houck; P L Deininger; C W Schmid
Journal: Proc Natl Acad Sci U S A Date: 1980-03 Impact factor: 11.205

9. Detection of a raf-related and two other transforming DNA sequences in human tumors maintained in nude mice.

Authors: M Fukui; T Yamamoto; S Kawai; K Maruo; K Toyoshima
Journal: Proc Natl Acad Sci U S A Date: 1985-09 Impact factor: 11.205

10. Structure and biological activity of human homologs of the raf/mil oncogene.

Authors: T I Bonner; S B Kerby; P Sutrave; M A Gunnell; G Mark; U R Rapp
Journal: Mol Cell Biol Date: 1985-06 Impact factor: 4.272

57 in total

1. Saccharomyces cerevisiae GATA sequences function as TATA elements during nitrogen catabolite repression and when Gln3p is excluded from the nucleus by overproduction of Ure2p.

Authors: K H Cox; R Rai; M Distler; J R Daugherty; J A Coffman; T G Cooper
Journal: J Biol Chem Date: 2000-06-09 Impact factor: 5.157

2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

Authors: Q H Zhang; M Ye; X Y Wu; S X Ren; M Zhao; C J Zhao; G Fu; Y Shen; H Y Fan; G Lu; M Zhong; X R Xu; Z G Han; J W Zhang; J Tao; Q H Huang; J Zhou; G X Hu; J Gu; S J Chen; Z Chen
Journal: Genome Res Date: 2000-10 Impact factor: 9.043

The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene.

1. The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1.

2. 3' non-coding region sequences in eukaryotic messenger RNA.

3. A catalogue of splice junction sequences.

4. A simple method for displaying the hydropathic character of a protein.

5. The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

6. Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins.

7. Molecular cloning of an activated human oncogene, homologous to v-raf, from primary stomach cancer.

8. Ubiquitous, interspersed repeated sequences in mammalian genomes.

9. Detection of a raf-related and two other transforming DNA sequences in human tumors maintained in nude mice.

10. Structure and biological activity of human homologs of the raf/mil oncogene.

1. Saccharomyces cerevisiae GATA sequences function as TATA elements during nitrogen catabolite repression and when Gln3p is excluded from the nucleus by overproduction of Ure2p.

2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

3. The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity.

4. 95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site.

5. A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans.

6. Molecular organization of the human Raf-1 promoter region.

7. Structure and transforming potential of the human cot oncogene encoding a putative protein kinase.

8. Induction of raf-1 protein immunoreactivity in guinea pig hippocampal slices during the in vitro maintenance.

9. Autoregulation of the Raf-1 serine/threonine kinase.

10. Actively transcribed genes in the raf oncogene group, located on the X chromosome in mouse and human.