Literature DB >> 30034589

High Affinity Neutral Bodipy Fluorophores for Mitochondrial Tracking.

Thumuganti Gayathri1,2, Santosh Karnewar3,2, Srigiridhar Kotamraju3,2, Surya Prakash Singh1,2.   

Abstract

We report the first high affinity neutral Bodipy fluorophores for selective imaging of mitochondria with notable sensitivity (∼100 nM) and insignificant cytotoxicity even at very high concentration (∼100 μM), when tested against HeLa cells. Further, these fluorophores are chemically robust and require no special conditions for storage.

Entities:  

Year:  2018        PMID： 30034589      PMCID： PMC6047038          DOI： 10.1021/acsmedchemlett.8b00022

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


  24 in total

1.  Intracellular imaging of organelles with new water-soluble benzophenoxazine dyes.

Authors:  Jiney Jose; Aurore Loudet; Yuichiro Ueno; Rola Barhoumi; Robert C Burghardt; Kevin Burgess
Journal:  Org Biomol Chem       Date:  2010-03-03       Impact factor: 3.876

Review 2.  Targeting lipophilic cations to mitochondria.

Authors:  Michael P Murphy
Journal:  Biochim Biophys Acta       Date:  2008-04-08

3.  Mitochondria-Localized Fluorescent BODIPY-Platinum Conjugate.

Authors:  Tingting Sun; Xingang Guan; Min Zheng; Xiabin Jing; Zhigang Xie
Journal:  ACS Med Chem Lett       Date:  2015-02-11       Impact factor: 4.345

4.  Structurally optimised BODIPY derivatives for imaging of mitochondrial dysfunction in cancer and heart cells.

Authors:  Shubhanchi Nigam; Benjamin P Burke; Laura H Davies; Juozas Domarkas; Jennifer F Wallis; Paul G Waddell; Jennifer S Waby; David M Benoit; Anne-Marie Seymour; Christopher Cawthorne; Lee J Higham; Stephen J Archibald
Journal:  Chem Commun (Camb)       Date:  2016-05-24       Impact factor: 6.222

Review 5.  Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications.

Authors:  Jacek Zielonka; Joy Joseph; Adam Sikora; Micael Hardy; Olivier Ouari; Jeannette Vasquez-Vivar; Gang Cheng; Marcos Lopez; Balaraman Kalyanaraman
Journal:  Chem Rev       Date:  2017-06-27       Impact factor: 60.622

6.  In vitro and in vivo photocytotoxicity of boron dipyrromethene derivatives for photodynamic therapy.

Authors:  Siang Hui Lim; Cliferson Thivierge; Patrycja Nowak-Sliwinska; Junyan Han; Hubert van den Bergh; Georges Wagnières; Kevin Burgess; Hong Boon Lee
Journal:  J Med Chem       Date:  2010-04-08       Impact factor: 7.446

7.  A BODIPY-based fluorescent dye for mitochondria in living cells, with low cytotoxicity and high photostability.

Authors:  Si Zhang; Tong Wu; Jiangli Fan; Zhiyong Li; Na Jiang; Jingyun Wang; Bairui Dou; Shiguo Sun; Fengling Song; Xiaojun Peng
Journal:  Org Biomol Chem       Date:  2012-12-11       Impact factor: 3.876

8.  Long-wavelength, photostable, two-photon excitable BODIPY fluorophores readily modifiable for molecular probes.

Authors:  Xinfu Zhang; Yi Xiao; Jing Qi; Junle Qu; Bosung Kim; Xiling Yue; Kevin D Belfield
Journal:  J Org Chem       Date:  2013-09-11       Impact factor: 4.354

9.  Mitochondrial uncoupler FCCP activates proton conductance but does not block store-operated Ca(2+) current in liver cells.

Authors:  Minh-Son To; Edoardo C Aromataris; Joel Castro; Michael L Roberts; Greg J Barritt; Grigori Y Rychkov
Journal:  Arch Biochem Biophys       Date:  2010-01-11       Impact factor: 4.013

10.  A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

Authors:  A Cossarizza; M Baccarani-Contri; G Kalashnikova; C Franceschi
Journal:  Biochem Biophys Res Commun       Date:  1993-11-30       Impact factor: 3.575
View more
  2 in total

1.  Two-photon excitable boron complex based on tridentate imidazo[1,5-a]pyridine ligand for heavy-atom-free mitochondria-targeted photodynamic therapy.

Authors:  Keita Hoshi; Masami Itaya; Koki Tahara; Airi Matsumoto; Atsuhi Tabata; Hideaki Nagamune; Yasushi Yoshida; Eiji Hase; Takeo Minamikawa; Takeshi Yasui; Tetsuro Katayama; Akihiro Furube; Keiji Minagawa; Yasushi Imada; Fumitoshi Yagishita
Journal:  RSC Adv       Date:  2021-08-02       Impact factor: 3.361

2.  Fine-tuning the electronic structure of heavy-atom-free BODIPY photosensitizers for fluorescence imaging and mitochondria-targeted photodynamic therapy.

Authors:  Sujie Qi; Nahyun Kwon; Yubin Yim; Van-Nghia Nguyen; Juyoung Yoon
Journal:  Chem Sci       Date:  2020-03-17       Impact factor: 9.825
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.