Literature DB >> 23229051

A BODIPY-based fluorescent dye for mitochondria in living cells, with low cytotoxicity and high photostability.

Si Zhang1, Tong Wu, Jiangli Fan, Zhiyong Li, Na Jiang, Jingyun Wang, Bairui Dou, Shiguo Sun, Fengling Song, Xiaojun Peng.   

Abstract

A BODIPY-based dye, OBEP, has been developed to act as a mitochondrial fluorescence probe. This dye is of high stability, low toxicity and insensitive in a pH range as wide as pH 2-10. Its uptake into mitochondria is independent of mitochondrial membrane potential in living cells. OBEP can label swollen mitochondria resulting from different degrees of cell damage in light and resist fading even after 12 h of incubation.

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Year:  2012        PMID: 23229051     DOI: 10.1039/c2ob26911b

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  10 in total

1.  High Affinity Neutral Bodipy Fluorophores for Mitochondrial Tracking.

Authors:  Thumuganti Gayathri; Santosh Karnewar; Srigiridhar Kotamraju; Surya Prakash Singh
Journal:  ACS Med Chem Lett       Date:  2018-06-20       Impact factor: 4.345

2.  Synthesis and Photochemical Properties of 2,3;5,6-bis(cyclohexano)-BODIPY.

Authors:  Anna Yu Kritskaya; Natalia A Bumagina; Elena V Antina; Alexander A Ksenofontov; Mikhail B Berezin; Alexander S Semeikin
Journal:  J Fluoresc       Date:  2017-12-27       Impact factor: 2.217

3.  Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response.

Authors:  Nadiya Romanova; Julian Schmitz; Marie Strakeljahn; Alexander Grünberger; Janina Bahnemann; Thomas Noll
Journal:  Cells       Date:  2022-05-27       Impact factor: 7.666

Review 4.  Contributions of academic laboratories to the discovery and development of chemical biology tools.

Authors:  Donna M Huryn; Lynn O Resnick; Peter Wipf
Journal:  J Med Chem       Date:  2013-05-31       Impact factor: 7.446

5.  Detection of analytes in mitochondria without interference from other sites based on an innovative ratiometric fluorophore.

Authors:  Tian-Bing Ren; Qian-Ling Zhang; Dongdong Su; Xing-Xing Zhang; Lin Yuan; Xiao-Bing Zhang
Journal:  Chem Sci       Date:  2018-05-22       Impact factor: 9.825

6.  GlycoBODIPYs: Sugars Serving as a Natural Stock for Water-soluble Fluorescent Probes of Complex Chiral Morphology.

Authors:  Lukas J Patalag; Somayeh Ahadi; Olesia Lashchuk; Peter G Jones; Simon Ebbinghaus; Daniel B Werz
Journal:  Angew Chem Int Ed Engl       Date:  2021-03-17       Impact factor: 15.336

7.  A Comparison of the Photophysical, Electrochemical and Cytotoxic Properties of meso-(2-, 3- and 4-Pyridyl)-BODIPYs and Their Derivatives.

Authors:  Caroline Ndung'u; Daniel J LaMaster; Simran Dhingra; Nathan H Mitchell; Petia Bobadova-Parvanova; Frank R Fronczek; Noémie Elgrishi; Maria da Graça H Vicente
Journal:  Sensors (Basel)       Date:  2022-07-07       Impact factor: 3.847

8.  Green-Light Activatable BODIPY and Coumarin 5'-Caps for Oligonucleotide Photocaging.

Authors:  Janik Kaufmann; Patricia Müller; Eleni Andreadou; Alexander Heckel
Journal:  Chemistry       Date:  2022-05-17       Impact factor: 5.020

9.  NIR-emitting styryl dyes with large Stokes' shifts for imaging application: From cellular plasma membrane, mitochondria to Zebrafish neuromast.

Authors:  Dipendra Dahal; Krishna R Ojha; Sabita Pokhrel; Sailaja Paruchuri; Michael Konopka; Qin Liu; Yi Pang
Journal:  Dyes Pigm       Date:  2021-07-06       Impact factor: 5.122

10.  Structurally Characterized BODIPY-Appended Oxidovanadium(IV) β-Diketonates for Mitochondria-Targeted Photocytotoxicity.

Authors:  Utso Bhattacharyya; Brijesh K Verma; Rupak Saha; Nandini Mukherjee; Md Kausar Raza; Somarupa Sahoo; Paturu Kondaiah; Akhil R Chakravarty
Journal:  ACS Omega       Date:  2020-02-24
  10 in total

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