| Literature DB >> 30011777 |
Michael A Borger1, Paul W M Fedak2, Elizabeth H Stephens3, Thomas G Gleason4, Evaldas Girdauskas5, John S Ikonomidis6, Ali Khoynezhad7, Samuel C Siu8, Subodh Verma9, Michael D Hope10, Duke E Cameron11, Donald F Hammer12, Joseph S Coselli13, Marc R Moon14, Thoralf M Sundt15, Alex J Barker16, Michael Markl17, Alessandro Della Corte18, Hector I Michelena19, John A Elefteriades20.
Abstract
Bicuspid aortic valve disease is the most common congenital cardiac disorder, being present in 1% to 2% of the general population. Associated aortopathy is a common finding in patients with bicuspid aortic valve disease, with thoracic aortic dilation noted in approximately 40% of patients in referral centers. Several previous consensus statements and guidelines have addressed the management of bicuspid aortic valve-associated aortopathy, but none focused entirely on this disease process. The current guidelines cover all major aspects of bicuspid aortic valve aortopathy, including natural history, phenotypic expression, histology and molecular pathomechanisms, imaging, indications for surgery, surveillance, and follow-up, and recommendations for future research. It is intended to provide clinicians with a current and comprehensive review of bicuspid aortic valve aortopathy and to guide the daily management of these complex patients.Entities:
Mesh：
Year: 2018 PMID： 30011777 PMCID： PMC6413866 DOI： 10.1016/j.jtcvs.2018.02.115
Source DB: PubMed Journal: J Thorac Cardiovasc Surg ISSN： 0022-5223 Impact factor: 5.209