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Literature DB >> 29999552

Regulation and functions of MicroRNA-149 in human cancers.

Yingru Zhi¹, Hao Zhou², Abudoureyimu Mubalake¹, Ying Chen¹, Bei Zhang², Kai Zhang¹, Xiaoyuan Chu¹, Rui Wang¹.

Abstract

MicroRNAs are small non-coding RNAs that play critical roles in the regulatory mechanisms involving cell differentiation, proliferation, apoptosis and tumorigenesis. Recent research efforts have been conducted to apply these discoveries into clinical functions, including the early diagnosis and therapeutic outcome of patients with cancer. Previous studies have shown that microRNA-149 (miR-149) is dysregulated in various human cancers and exerts its effects on tumorigenesis and tumour progression. In this review, we summarized the potential roles of miR-149 dysregulation and its target genes during tumorigenesis and clinical treatment of human cancers.

Entities: Disease Gene Species

Keywords: cancer; chemotherapy; diagnosis; dysregulation; miR-149; prognosis

Mesh：

Substances：

Year: 2018 PMID： 29999552 PMCID： PMC6528861 DOI： 10.1111/cpr.12465

Source DB: PubMed Journal: Cell Prolif ISSN： 0960-7722 Impact factor: 6.831

106 in total

1. miR-149 promotes human osteocarcinoma progression via targeting bone morphogenetic protein 9 (BMP9).

Authors: Zikang Xie; Jianda Xu; Libo Peng; Yi Gao; Hong Zhao; Yuxing Qu
Journal: Biotechnol Lett Date: 2017-09-27 Impact factor: 2.461

Review 2. Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants.

Authors: Jr-Shiuan Yang; Eric C Lai
Journal: Mol Cell Date: 2011-09-16 Impact factor: 17.970

3. The miR-149 rs2292832 T/C polymorphism may decrease digestive cancer susceptibility: an updated meta-analysis.

Authors: Lin Li; Tao Liu; Zuo Li; Lixin Zhang; Zhiqiang Zhang
Journal: Int J Clin Exp Med Date: 2015-09-15

Review 4. Targeting microRNAs in cancer: rationale, strategies and challenges.

Authors: Ramiro Garzon; Guido Marcucci; Carlo M Croce
Journal: Nat Rev Drug Discov Date: 2010-10 Impact factor: 84.694

5. Grade-specific expression profiles of miRNAs/mRNAs and docking study in human grade I-III astrocytomas.

Authors: Dan Li; Pan Chen; Xia-Yu Li; Li-Yang Zhang; Wei Xiong; Ming Zhou; Lan Xiao; Fang Zeng; Xiao-Ling Li; Ming-Hua Wu; Gui-Yuan Li
Journal: OMICS Date: 2011-10

6. MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma.

Authors: Lei Jin; Wang Lai Hu; Chen Chen Jiang; Jia Xu Wang; Chuan Chun Han; Ping Chu; Lin Jie Zhang; Rick F Thorne; James Wilmott; Richard A Scolyer; Peter Hersey; Xu Dong Zhang; Mian Wu
Journal: Proc Natl Acad Sci U S A Date: 2011-09-06 Impact factor: 11.205

7. An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma.

Authors: Zhaohui Luo; Liyang Zhang; Zheng Li; Xiayu Li; Gang Li; Haibo Yu; Chen Jiang; Yafei Dai; Xiaofang Guo; Juanjuan Xiang; Guiyuan Li
Journal: BMC Med Genomics Date: 2012-01-19 Impact factor: 3.063

8. Targeting of GIT1 by miR-149* in breast cancer suppresses cell proliferation and metastasis in vitro and tumor growth in vivo.

Authors: Yan Dong; Cai Chang; Jingtian Liu; Jinwei Qiang
Journal: Onco Targets Ther Date: 2017-12-11 Impact factor: 4.147

9. miR149 rs71428439 polymorphism and risk of clear cell renal cell carcinoma: a case-control study.

Authors: Zhigang Wang; Meng Wei; Yi Ren; Hua Liu; Meng Wang; Kehui Shi; Hongli Jiang
Journal: Tumour Biol Date: 2014-09-12

10. MicroRNA-dependent regulation of transcription in non-small cell lung cancer.

Authors: Sonia Molina-Pinelo; Gabriel Gutiérrez; Maria Dolores Pastor; Marta Hergueta; Gema Moreno-Bueno; Rocío García-Carbonero; Ana Nogal; Rocío Suárez; Ana Salinas; Francisco Pozo-Rodríguez; Fernando Lopez-Rios; Maria Teresa Agulló-Ortuño; Irene Ferrer; Asunción Perpiñá; José Palacios; Amancio Carnero; Luis Paz-Ares
Journal: PLoS One Date: 2014-03-13 Impact factor: 3.240

8 in total

Review 1. Regulation and functions of MicroRNA-149 in human cancers.

Authors: Yingru Zhi; Hao Zhou; Abudoureyimu Mubalake; Ying Chen; Bei Zhang; Kai Zhang; Xiaoyuan Chu; Rui Wang
Journal: Cell Prolif Date: 2018-07-12 Impact factor: 6.831

2. Histone Deacetylase Inhibitor Sensitizes ERCC1-High Non-small-Cell Lung Cancer Cells to Cisplatin via Regulating miR-149.

Authors: Yuwen He; Danyang Chen; Yanmei Yi; Shanshan Zeng; Shuang Liu; Pan Li; Hui Xie; Pengjiu Yu; Guanmin Jiang; Hao Liu
Journal: Mol Ther Oncolytics Date: 2020-05-08 Impact factor: 7.200

3. Uric acid induced hepatocytes lipid accumulation through regulation of miR-149-5p/FGF21 axis.

Authors: Shenghui Chen; Dan Chen; Hua Yang; Xinyu Wang; Jinghua Wang; Chengfu Xu
Journal: BMC Gastroenterol Date: 2020-02-18 Impact factor: 3.067

4. Genetic Variation in MicroRNA-423 Promotes Proliferation, Migration, Invasion, and Chemoresistance in Breast Cancer Cells.

Authors: Sebastian Morales-Pison; Lilian Jara; Valentina Carrasco; Cristian Gutiérrez-Vera; José Miguel Reyes; Patricio Gonzalez-Hormazabal; Leandro J Carreño; Julio C Tapia; Héctor R Contreras
Journal: Int J Mol Sci Date: 2021-12-29 Impact factor: 5.923

8. Health influenced by genetics: A first comprehensive analysis of breast cancer high and moderate penetrance susceptibility genes in the Tunisian population.

Authors: Maroua Boujemaa; Najah Mighri; Lotfi Chouchane; Mohamed Samir Boubaker; Sonia Abdelhak; Hamouda Boussen; Yosr Hamdi
Journal: PLoS One Date: 2022-03-25 Impact factor: 3.240