Literature DB >> 2999420

Polyomavirus middle T protein encoded by a retrovirus transforms nonestablished chicken embryo cells.

P L Kaplan, S Simon, W Eckhart.   

Abstract

A murine retrovirus encoding the middle T protein of polyomavirus infected and transformed nonestablished chicken embryo cells. The infected cultures formed colonies in soft agar-containing medium and released infectious transforming virus. Middle T protein expressed in the transformed chicken cells associated with p60c-src and, in immunoprecipitates, enhanced the tyrosine protein kinase activity of p60c-src.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2999420      PMCID： PMC252678     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  18 in total

1.  Structural and functional modification of pp60c-src associated with polyoma middle tumor antigen from infected or transformed cells.

Authors:  C A Cartwright; M A Hutchinson; W Eckhart
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

2.  Characterization of polyoma mutants with altered middle and large T-antigens.

Authors:  G Magnusson; M G Nilsson; S M Dilworth; N Smolar
Journal:  J Virol       Date:  1981-09       Impact factor: 5.103

3.  Early mutants of polyoma virus (dl8 and dl23) with altered transformation properties: is polyoma virus middle T antigen a transforming gene product?

Authors:  B E Griffin; Y Ito; U Novak; N Spurr; S Dilworth; N Smolar; R Pollack; K Smith; D B Rifkin
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1980

4.  The roles of individual polyoma virus early proteins in oncogenic transformation.

Authors:  M Rassoulzadegan; A Cowie; A Carr; N Glaichenhaus; R Kamen; F Cuzin
Journal:  Nature       Date:  1982-12-23       Impact factor: 49.962

5.  An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates.

Authors:  W Eckhart; M A Hutchinson; T Hunter
Journal:  Cell       Date:  1979-12       Impact factor: 41.582

6.  5-Bromo-2'-deoxyuridine potentiation of transformation of rat-embryo cells induced in vitro by 3-methylcholanthrene: induction of rat leukemia virus gs antigen in transformed cells.

Authors:  A E Freeman; R V Gilden; M L Vernon; R G Wolford; P E Hugunin; R J Huebner
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

7.  Amphotropic host range of naturally occuring wild mouse leukemia viruses.

Authors:  S Rasheed; M B Gardner; E Chan
Journal:  J Virol       Date:  1976-07       Impact factor: 5.103

8.  Construction and isolation of a transforming murine retrovirus containing the src gene of Rous sarcoma virus.

Authors:  S M Anderson; E M Scolnick
Journal:  J Virol       Date:  1983-05       Impact factor: 5.103

9.  Polyoma virus transforming protein associates with the product of the c-src cellular gene.

Authors:  S A Courtneidge; A E Smith
Journal:  Nature       Date:  1983 Jun 2-8       Impact factor: 49.962

10.  Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein.

Authors:  R Treisman; U Novak; J Favaloro; R Kamen
Journal:  Nature       Date:  1981-08-13       Impact factor: 49.962
View more
  15 in total

1.  A retrovirus carrying the polyomavirus middle T gene induces acute thrombocythemic myeloproliferative disease in mice.

Authors:  A Fusco; G Portella; M Grieco; G Tajana; G Di Minno; N Polli; A Pinto
Journal:  J Virol       Date:  1988-01       Impact factor: 5.103

2.  Interactions between polyomavirus medium T antigen and three cellular proteins of 88, 61, and 37 kilodaltons.

Authors:  T Grussenmeyer; A Carbone-Wiley; K H Scheidtmann; G Walter
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

3.  Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.

Authors:  C A Cartwright; P L Kaplan; J A Cooper; T Hunter; W Eckhart
Journal:  Mol Cell Biol       Date:  1986-05       Impact factor: 4.272

4.  A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity.

Authors:  B J Druker; L E Ling; B Cohen; T M Roberts; B S Schaffhausen
Journal:  J Virol       Date:  1990-09       Impact factor: 5.103

5.  Characterization of pp85, a target of oncogenes and growth factor receptors.

Authors:  B Cohen; Y X Liu; B Druker; T M Roberts; B S Schaffhausen
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

6.  Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro.

Authors:  W C Morgan; D R Kaplan; D C Pallas; T M Roberts
Journal:  J Virol       Date:  1988-09       Impact factor: 5.103

7.  Generation of a large library of point mutations in polyoma middle T antigen.

Authors:  B J Druker; T M Roberts
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

8.  p56lck protein-tyrosine kinase is cytoskeletal and does not bind to polyomavirus middle T antigen.

Authors:  R R Louie; C S King; A MacAuley; J D Marth; R M Perlmutter; W Eckhart; J A Cooper
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

9.  Overproduction of polyomavirus middle T antigen in mammalian cells through the use of an adenovirus vector.

Authors:  D Davidson; J A Hassell
Journal:  J Virol       Date:  1987-04       Impact factor: 5.103

10.  Polyomavirus middle T-antigen NPTY mutants.

Authors:  B J Druker; L Sibert; T M Roberts
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.