Literature DB >> 29989486

2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest.

Emily Arentson-Lantz, Elfego Galvan, Adam Wacher, Christopher S Fry, Douglas Paddon-Jones.   

Abstract

Physical activity in an inpatient setting is often limited to brief periods of walking. For healthy adults, public health agencies recommend a minimum of 150 min/week of moderate-intensity exercise. The authors sought to determine if meeting this activity threshold, in the absence of incidental activities of daily living, could protect skeletal muscle health during bed rest. Healthy older adults (68 ± 2 years) were randomized to 7-day bed rest with (STEP, n = 7) or without (CON, n = 10) a 2,000 steps/day intervention. Performing 2018 ± 4 steps/day did not prevent the loss of lean leg mass and had no beneficial effect on aerobic capacity, strength, or muscle fiber volume. However, the insulin response to an oral glucose challenge was preserved. Performing a block of 2,000 steps/day, in the absence of incidental activities of daily living, was insufficient to fully counter the catabolic effects of bed rest in healthy older adults.

Entities:  

Keywords:  atrophy; inactivity; muscle function; physical activity

Mesh:

Year:  2019        PMID: 29989486      PMCID: PMC6710835          DOI: 10.1123/japa.2018-0093

Source DB:  PubMed          Journal:  J Aging Phys Act        ISSN: 1063-8652            Impact factor:   1.961


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