Literature DB >> 33630061

Practical applications of whey protein in supporting skeletal muscle maintenance, recovery, and reconditioning.

Emily J Arentson-Lantz1, Sean Kilroe1,2.   

Abstract

Like humans, many companion animals experience a gradual decline in skeletal muscle mass and function during later years of life. This process, analogous to sarcopenia in humans, increases risk for morbidity and mortality. Periods of reduced activity due to injury or illness, followed by an incomplete recovery, can accelerate the loss of muscle mass and function. Emerging research from human studies suggests that moderate amounts of high-quality protein may attenuate the loss of muscle, while preventing accumulation of fat during periods of disuse. Whey protein is a consumer-friendly and readily available source of high-quality protein. It supports skeletal muscle maintenance during normal aging and may also provide anabolic support during periods of illness, injury, and recovery. Ongoing research efforts continue to refine our understanding of how protein quality, quantity, and meal timing can be optimized to support retention of muscle mass and function during aging. Priority research areas include supplementation with high-quality protein during illness/injury to stimulate anabolism by targeting molecular mechanisms that regulate skeletal muscle metabolism.
© The Author(s) 2021. Published by Oxford University Press on behalf of the American Society of Animal Science. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  aging; atrophy; disuse; humans; whey protein skeletal muscle

Mesh:

Substances:

Year:  2021        PMID: 33630061      PMCID: PMC8075117          DOI: 10.1093/jas/skab060

Source DB:  PubMed          Journal:  J Anim Sci        ISSN: 0021-8812            Impact factor:   3.159


  59 in total

1.  Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men.

Authors:  Suzanne Verhoeven; Kristof Vanschoonbeek; Lex B Verdijk; René Koopman; Will K W H Wodzig; Paul Dendale; Luc J C van Loon
Journal:  Am J Clin Nutr       Date:  2009-03-25       Impact factor: 7.045

2.  Effects of Milk Proteins Supplementation in Older Adults Undergoing Resistance Training: A Meta-Analysis of Randomized Control Trials.

Authors:  K Hidayat; G-C Chen; Y Wang; Z Zhang; X Dai; I M Y Szeto; L-Q Qin
Journal:  J Nutr Health Aging       Date:  2018       Impact factor: 4.075

3.  A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly.

Authors:  Christos S Katsanos; Hisamine Kobayashi; Melinda Sheffield-Moore; Asle Aarsland; Robert R Wolfe
Journal:  Am J Physiol Endocrinol Metab       Date:  2006-02-28       Impact factor: 4.310

4.  Improving Dietary Protein Quality Reduces the Negative Effects of Physical Inactivity on Body Composition and Muscle Function.

Authors:  Emily J Arentson-Lantz; Elfego Galvan; Jennifer Ellison; Adam Wacher; Douglas Paddon-Jones
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2019-09-15       Impact factor: 6.053

5.  Skeletal muscle disuse atrophy is not attenuated by dietary protein supplementation in healthy older men.

Authors:  Marlou L Dirks; Benjamin T Wall; Rachel Nilwik; Daniëlle H J M Weerts; Lex B Verdijk; Luc J C van Loon
Journal:  J Nutr       Date:  2014-06-11       Impact factor: 4.798

6.  Two weeks of reduced activity decreases leg lean mass and induces "anabolic resistance" of myofibrillar protein synthesis in healthy elderly.

Authors:  Leigh Breen; Keith A Stokes; Tyler A Churchward-Venne; Daniel R Moore; Stephen K Baker; Kenneth Smith; Philip J Atherton; Stuart M Phillips
Journal:  J Clin Endocrinol Metab       Date:  2013-04-15       Impact factor: 5.958

7.  Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review.

Authors:  W Kyle Mitchell; John Williams; Philip Atherton; Mike Larvin; John Lund; Marco Narici
Journal:  Front Physiol       Date:  2012-07-11       Impact factor: 4.566

8.  Exceptional longevity and potential determinants of successful ageing in a cohort of 39 Labrador retrievers: results of a prospective longitudinal study.

Authors:  Vicki Jean Adams; Penny Watson; Stuart Carmichael; Stephen Gerry; Johanna Penell; David Mark Morgan
Journal:  Acta Vet Scand       Date:  2016-05-11       Impact factor: 1.695

Review 9.  Optimizing Adult Protein Intake During Catabolic Health Conditions.

Authors:  Stuart M Phillips; Douglas Paddon-Jones; Donald K Layman
Journal:  Adv Nutr       Date:  2020-07-01       Impact factor: 8.701

10.  Signalling pathways regulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway.

Authors:  M Sandri; L Barberi; A Y Bijlsma; B Blaauw; K A Dyar; G Milan; C Mammucari; C G M Meskers; G Pallafacchina; A Paoli; D Pion; M Roceri; V Romanello; A L Serrano; L Toniolo; L Larsson; A B Maier; P Muñoz-Cánoves; A Musarò; M Pende; C Reggiani; R Rizzuto; S Schiaffino
Journal:  Biogerontology       Date:  2013-05-19       Impact factor: 4.277

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