Literature DB >> 29984446

Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis.

Fabio Barra1,2, Lorenzo Ferro Desideri1,2, Simone Ferrero1,2.   

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Year:  2018        PMID： 29984446      PMCID： PMC6086976          DOI： 10.1111/bph.14391

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


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  6 in total

1.  Everolimus as an mTOR Inhibitor Suppresses Endometriotic Implants: an Experimental Rat Study.

Authors:  T Kacan; C Yildiz; S Baloglu Kacan; M Seker; H Ozer; A Cetin
Journal:  Geburtshilfe Frauenheilkd       Date:  2017-01       Impact factor: 2.915

2.  Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis.

Authors:  Fabio Barra; Lorenzo Ferro Desideri; Simone Ferrero
Journal:  Br J Pharmacol       Date:  2018-07-08       Impact factor: 8.739

3.  In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis: autophagy may be required for regrowth of endometriosis.

Authors:  Sachiko Matsuzaki; Jean-Luc Pouly; Michel Canis
Journal:  Br J Pharmacol       Date:  2018-04-16       Impact factor: 8.739

Review 4.  Targeting the PI3K pathway in cancer: are we making headway?

Authors:  Filip Janku; Timothy A Yap; Funda Meric-Bernstam
Journal:  Nat Rev Clin Oncol       Date:  2018-03-06       Impact factor: 66.675

Review 5.  Influence of AKT on progesterone action in endometrial diseases.

Authors:  Irene I Lee; J Julie Kim
Journal:  Biol Reprod       Date:  2014-08-06       Impact factor: 4.285

Review 6.  Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases.

Authors:  K D Rainsford; Ann L Parke; Matthew Clifford-Rashotte; W F Kean
Journal:  Inflammopharmacology       Date:  2015-08-06       Impact factor: 5.093
  6 in total
  16 in total

1.  Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis.

Authors:  Fabio Barra; Lorenzo Ferro Desideri; Simone Ferrero
Journal:  Br J Pharmacol       Date:  2018-07-08       Impact factor: 8.739

2.  Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis.

Authors:  Kumaravel Mohankumar; Xi Li; Nuri Sung; Yeon Jean Cho; Sang Jun Han; Stephen Safe
Journal:  Endocrinology       Date:  2020-04-01       Impact factor: 4.736

3.  Effect of miR-194-5p regulating STAT1/mTOR signaling pathway on the biological characteristics of ectopic endometrial cells from mice.

Authors:  Qian Zhao; Bing Han; Ying Zhang; Ke Su; Chunfang Wang; Panpan Hai; Aiping Bian; Ruixia Guo
Journal:  Am J Transl Res       Date:  2020-10-15       Impact factor: 4.060

4.  Inhibition of erythropoietin-producing hepatoma receptor B4 (EphB4) signalling suppresses the vascularisation and growth of endometriotic lesions.

Authors:  Jeannette Rudzitis-Auth; Sophia A Fuß; Vivien Becker; Michael D Menger; Matthias W Laschke
Journal:  Br J Pharmacol       Date:  2020-04-12       Impact factor: 8.739

Review 5.  Role of mTOR Signaling in Female Reproduction.

Authors:  Zaixin Guo; Qi Yu
Journal:  Front Endocrinol (Lausanne)       Date:  2019-10-09       Impact factor: 5.555

6.  EPHA3 enhances macrophage autophagy and apoptosis by disrupting the mTOR signaling pathway in mice with endometriosis.

Authors:  Hongmei Xu; Yongmei Gao; Yang Shu; Yi Wang; Qingyang Shi
Journal:  Biosci Rep       Date:  2019-07-30       Impact factor: 3.840

7.  MicroRNA-342 Promotes the Malignant-Like Phenotype of Endometrial Stromal Cells via Regulation of Annexin A2.

Authors:  Dan Sun; Yiting Wang; Li Wang; Xin Guo
Journal:  Anal Cell Pathol (Amst)       Date:  2021-05-15       Impact factor: 2.916

Review 8.  Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing.

Authors:  Mila Maidarti; Richard A Anderson; Evelyn E Telfer
Journal:  Cells       Date:  2020-01-14       Impact factor: 6.600

9.  Transcriptome meta-analysis reveals differences of immune profile between eutopic endometrium from stage I-II and III-IV endometriosis independently of hormonal milieu.

Authors:  Omero Benedicto Poli-Neto; Juliana Meola; Julio Cesar Rosa-E-Silva; Daniel Tiezzi
Journal:  Sci Rep       Date:  2020-01-15       Impact factor: 4.379

10.  Role of lncRNA FTX in invasion, metastasis, and epithelial-mesenchymal transition of endometrial stromal cells caused by endometriosis by regulating the PI3K/Akt signaling pathway.

Authors:  Huixiang Wang; Chengxiang Ni; Wei Xiao; Sulin Wang
Journal:  Ann Transl Med       Date:  2020-11
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