Literature DB >> 2997468

Structure of simian virus 40-adeno-associated virus recombinant genomes.

Z Grossman, K I Berns, E Winocour.   

Abstract

The structures of recombinant genomes formed by recombination between simian virus 40 (SV40) and adeno-associated virus 2 (AAV) DNAs after either DNA cotransfection or coinfection by virions were characterized. Two types of structures were found. Group A structures, found after cotransfection and in one of seven recombinants arising from coinfection, represented a simple deletion of SV40 sequences replaced by a slightly shorter AAV sequence. Group B structures were found in six of seven recombinants arising after virion coinfection. All contained either the left or right terminal sequences (approximately 250 to 450 bases) of the AAV genome adjacent to the SV40 origin of DNA replication. Only 350 to 650 bases (including the origin) remained of the SV40 sequence. The joined SV40-AAV sequences were present in the recombinant genome as a tandem repeat of a size that can be packaged into SV40 capsids.

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Year:  1985        PMID： 2997468      PMCID： PMC252600     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  39 in total

1.  Study of the fine structure of adeno-associated virus DNA with bacterial restriction endonucleases.

Authors:  K I Berns; J Kort; K H Fife; E W Grogan; I Spear
Journal:  J Virol       Date:  1975-09       Impact factor: 5.103

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  Linear simian virus 40 DNA fragments exhibit a propensity for rolling-circle replication.

Authors:  I Deichaite; Z Laver-Rudich; D Dorsett; E Winocour
Journal:  Mol Cell Biol       Date:  1985-07       Impact factor: 4.272

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Authors:  J H McCutchan; J S Pagano
Journal:  J Natl Cancer Inst       Date:  1968-08       Impact factor: 13.506

5.  Evidence for a single-stranded adenovirus-associated virus genome: formation of a DNA density hybrid on release of viral DNA.

Authors:  J A Rose; K I Berns; M D Hoggan; F J Koczot
Journal:  Proc Natl Acad Sci U S A       Date:  1969-11       Impact factor: 11.205

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Authors:  D T Denhardt
Journal:  Biochem Biophys Res Commun       Date:  1966-06-13       Impact factor: 3.575

7.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

8.  Concatemers of alternating plus and minus strands are intermediates in adenovirus-associated virus DNA synthesis.

Authors:  S E Straus; E D Sebring; J A Rose
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

9.  Structure of replicating simian virus 40 deoxyribonucleic acid molecules.

Authors:  E D Sebring; T J Kelly; M M Thoren; N P Salzman
Journal:  J Virol       Date:  1971-10       Impact factor: 5.103

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Authors:  S Lavi; E Winocour
Journal:  J Virol       Date:  1972-02       Impact factor: 5.103
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  9 in total

1.  High recombination rate of an Epstein-Barr virus-simian virus 40 hybrid shuttle vector in human cells.

Authors:  A Stary; M R James; A Sarasin
Journal:  J Virol       Date:  1989-09       Impact factor: 5.103

Review 2.  AAV: An Overview of Unanswered Questions.

Authors:  Kenneth I Berns; Nicholas Muzyczka
Journal:  Hum Gene Ther       Date:  2017-04       Impact factor: 5.695

3.  Adeno-Associated Virus Vector Mobilization, Risk Versus Reality.

Authors:  Liujiang Song; R Jude Samulski; Matthew L Hirsch
Journal:  Hum Gene Ther       Date:  2020-10       Impact factor: 5.695

4.  Directed integration of minute virus of mice DNA into episomes.

Authors:  J Corsini; J Tal; E Winocour
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

5.  Replication of adeno-associated virus in synchronized cells without the addition of a helper virus.

Authors:  B Yakobson; T Koch; E Winocour
Journal:  J Virol       Date:  1987-04       Impact factor: 5.103

6.  Identification and elimination of replication-competent adeno-associated virus (AAV) that can arise by nonhomologous recombination during AAV vector production.

Authors:  J M Allen; D J Debelak; T C Reynolds; A D Miller
Journal:  J Virol       Date:  1997-09       Impact factor: 5.103

7.  Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein.

Authors:  A Beaton; P Palumbo; K I Berns
Journal:  J Virol       Date:  1989-10       Impact factor: 5.103

8.  Recombinant junctions formed by site-specific integration of adeno-associated virus into an episome.

Authors:  C Giraud; E Winocour; K I Berns
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

9.  Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.

Authors:  R M Kotin; R M Linden; K I Berns
Journal:  EMBO J       Date:  1992-12       Impact factor: 11.598
  9 in total

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