Literature DB >> 2550677

Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein.

A Beaton1, P Palumbo, K I Berns.   

Abstract

The leftward two promoters of the adeno-associated virus (AAV) 2 genome were fused to reporter genes, and the constructs were used to transfect HeLa cells. The promoters functioned constitutively but were repressed in trans by the AAV rep gene product(s). The repression was relieved by adenovirus infection. Evidence which indicated an enhancer function for the inverted terminal repeat of the AAV-2 genome was also obtained.

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Year:  1989        PMID： 2550677      PMCID： PMC251068          DOI： 10.1128/JVI.63.10.4450-4454.1989

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

1.  Adeno-associated virus autointerference.

Authors:  B J Carter; C A Laughlin; L M de la Maza; M Myers
Journal:  Virology       Date:  1979-01-30       Impact factor: 3.616

Review 2.  Regulation of adeno-associated virus DNA replication.

Authors:  K I Berns; R M Kotin; M A Labow
Journal:  Biochim Biophys Acta       Date:  1988-12-20

3.  Definition of a novel promoter for the major adenovirus-associated virus mRNA.

Authors:  M R Green; R G Roeder
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

4.  Mapping of the 5' termini of two adeno-associated virus 2 RNAs in the left half of the genome.

Authors:  E W Lusby; K I Berns
Journal:  J Virol       Date:  1982-02       Impact factor: 5.103

5.  Nucleotide sequence and organization of the adeno-associated virus 2 genome.

Authors:  A Srivastava; E W Lusby; K I Berns
Journal:  J Virol       Date:  1983-02       Impact factor: 5.103

6.  DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

Authors:  M Wigler; A Pellicer; S Silverstein; R Axel; G Urlaub; L Chasin
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

7.  Recombination between simian virus 40 and adeno-associated virus: virion coinfection compared to DNA cotransfection.

Authors:  Z Grossman; E Winocour; K I Berns
Journal:  Virology       Date:  1984-04-15       Impact factor: 3.616

8.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

9.  Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product.

Authors:  J D Tratschin; J Tal; B J Carter
Journal:  Mol Cell Biol       Date:  1986-08       Impact factor: 4.272

10.  Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication.

Authors:  R M Buller; J E Janik; E D Sebring; J A Rose
Journal:  J Virol       Date:  1981-10       Impact factor: 5.103
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  72 in total

1.  Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins.

Authors:  J Wu; M D Davis; R A Owens
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

2.  Infection of primary cells by adeno-associated virus type 2 results in a modulation of cell cycle-regulating proteins.

Authors:  J Hermanns; A Schulze; P Jansen-Db1urr; J A Kleinschmidt; R Schmidt; H zur Hausen
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

3.  Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size.

Authors:  G E Tullis; T Shenk
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

Review 4.  Parvovirus replication.

Authors:  K I Berns
Journal:  Microbiol Rev       Date:  1990-09

5.  Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation.

Authors:  Faik N Musayev; Francisco Zarate-Perez; Martino Bardelli; Clayton Bishop; Emil F Saniev; R Michael Linden; Els Henckaerts; Carlos R Escalante
Journal:  Biochemistry       Date:  2015-09-14       Impact factor: 3.162

6.  High-level expression of adeno-associated virus (AAV) Rep78 or Rep68 protein is sufficient for infectious-particle formation by a rep-negative AAV mutant.

Authors:  C Hölscher; J A Kleinschmidt; A Bürkle
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

7.  Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 protein.

Authors:  S R Kyöstiö; R S Wonderling; R A Owens
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

8.  Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.

Authors:  D M McCarty; D J Pereira; I Zolotukhin; X Zhou; J H Ryan; N Muzyczka
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

9.  Characterization of cell lines that inducibly express the adeno-associated virus Rep proteins.

Authors:  Q Yang; F Chen; J P Trempe
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

10.  Interaction of the adeno-associated virus Rep protein with a sequence within the A palindrome of the viral terminal repeat.

Authors:  D M McCarty; J H Ryan; S Zolotukhin; X Zhou; N Muzyczka
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103
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