Literature DB >> 29967909

Energy landscape of polymorphic amyloid generation of β2-microglobulin revealed by calorimetry.

Misaki Kinoshita1, Yuxi Lin, Itoh Dai, Masaki Okumura, Natalia Markova, John E Ladbury, Fabio Sterpone, Young-Ho Lee.   

Abstract

Understanding of amyloid aggregation in terms of thermodynamics and kinetics is still limited. We herein examined the mechanism of β2-microglobulin amyloidogenesis using our unique method of isothermal titration calorimetry-based thermodynamic/kinetic measurements, and revealed the energy landscape of polymorphic amyloidogenesis under biological environment-mimicking conditions including shear forces and crowding effects.

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Year:  2018        PMID： 29967909     DOI： 10.1039/c8cc02718h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Zinc boosts EGCG's hIAPP amyloid Inhibition both in solution and membrane.

Authors:  Young-Ho Lee; Yuxi Lin; Sarah J Cox; Misaki Kinoshita; Bikash R Sahoo; Magdalena Ivanova; Ayyalusamy Ramamoorthy
Journal:  Biochim Biophys Acta Proteins Proteom       Date:  2018-11-22       Impact factor: 3.036

Review 2.  Proteins Do Not Replicate, They Precipitate: Phase Transition and Loss of Function Toxicity in Amyloid Pathologies.

Authors:  Kariem Ezzat; Andrea Sturchio; Alberto J Espay
Journal:  Biology (Basel)       Date:  2022-03-30

Review 3.  Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.

Authors:  Phuong H Nguyen; Ayyalusamy Ramamoorthy; Bikash R Sahoo; Jie Zheng; Peter Faller; John E Straub; Laura Dominguez; Joan-Emma Shea; Nikolay V Dokholyan; Alfonso De Simone; Buyong Ma; Ruth Nussinov; Saeed Najafi; Son Tung Ngo; Antoine Loquet; Mara Chiricotto; Pritam Ganguly; James McCarty; Mai Suan Li; Carol Hall; Yiming Wang; Yifat Miller; Simone Melchionna; Birgit Habenstein; Stepan Timr; Jiaxing Chen; Brianna Hnath; Birgit Strodel; Rakez Kayed; Sylvain Lesné; Guanghong Wei; Fabio Sterpone; Andrew J Doig; Philippe Derreumaux
Journal:  Chem Rev       Date:  2021-02-05       Impact factor: 60.622

4.  Bean Extract-Based Gargle for Efficient Diagnosis of Active COVID-19 Infection Using Rapid Antigen Tests.

Authors:  Joseph Kwon; Euna Ko; Se-Young Cho; Young-Ho Lee; Sangmi Jun; Kyuhong Lee; Eunha Hwang; Bipin Vaidya; Jeong-Hwan Hwang; Joo-Hee Hwang; Namsu Kim; Mi-Kyung Song; Hye-Yeon Kim; Dai Ito; Yuxi Lin; Eunae Jo; Kyeong Eun Yang; Hee-Chung Chung; Soyoung Cha; Dong Im Kim; Yoon-Sun Yi; Sung-Ho Yun; Sun Cheol Park; Sangmin Lee; Jong-Soon Choi; Dal Sik Kim; Duwoon Kim
Journal:  Microbiol Spectr       Date:  2022-02-16

5.  Biophysical elucidation of neural network and chemical regeneration of neural tissue.

Authors:  Takahiro Muraoka; Tomohide Saio; Masaki Okumura
Journal:  Biophys Physicobiol       Date:  2022-07-27
  5 in total

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