Literature DB >> 29943240

[Genetic testing to prevent sudden cardiac death].

B Stallmeyer1, S Dittmann1, E Schulze-Bahr2.   

Abstract

Successfully incorporating genetic testing into clinical practice to prevent sudden cardiac death (SCD) requires (1) appropriate recognition of an inherited cardiovascular condition, (2) identification of appropriate family members at risk and for genetic testing, (3) selection of the appropriate genetic test and information about the expected diagnostic yield, (4) understanding the complexity of result interpretation and distinct handling of incidental findings and (5) providing effective communication and medical advice regarding the genetic and medical results and implications to the patient and his family. Molecular autopsy in SCD victims will be of future importance to determine the cause of death. Interdisciplinary patient care should be provided in specialized centers with a high level of cardiogenetic expertise and is recommended to provide precise and individualized patient management.

Entities:  

Keywords:  Arrhythmias, cardiac; Autopsy, molecular; Cardiomyopathies; Genetic testing; Mutation

Mesh:

Year:  2018        PMID: 29943240     DOI: 10.1007/s00108-018-0462-x

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  104 in total

1.  Predicting arrhythmic risk in arrhythmogenic right ventricular cardiomyopathy: A systematic review and meta-analysis.

Authors:  Laurens P Bosman; Arjan Sammani; Cynthia A James; Julia Cadrin-Tourigny; Hugh Calkins; J Peter van Tintelen; Richard N W Hauer; Folkert W Asselbergs; Anneline S J M Te Riele
Journal:  Heart Rhythm       Date:  2018-02-03       Impact factor: 6.343

2.  Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives.

Authors:  Hanno L Tan; Nynke Hofman; Irene M van Langen; Allard C van der Wal; Arthur A M Wilde
Journal:  Circulation       Date:  2005-07-05       Impact factor: 29.690

3.  Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention.

Authors:  Barry J Maron; Jeffrey A Towbin; Gaetano Thiene; Charles Antzelevitch; Domenico Corrado; Donna Arnett; Arthur J Moss; Christine E Seidman; James B Young
Journal:  Circulation       Date:  2006-03-27       Impact factor: 29.690

4.  Long-term follow-up of patients with short QT syndrome.

Authors:  Carla Giustetto; Rainer Schimpf; Andrea Mazzanti; Chiara Scrocco; Philippe Maury; Olli Anttonen; Vincent Probst; Jean-Jacques Blanc; Pascal Sbragia; Paola Dalmasso; Martin Borggrefe; Fiorenzo Gaita
Journal:  J Am Coll Cardiol       Date:  2011-08-02       Impact factor: 24.094

5.  Multiple Gene Variants in Hypertrophic Cardiomyopathy in the Era of Next-Generation Sequencing.

Authors:  Charlotte Burns; Richard D Bagnall; Lien Lam; Christopher Semsarian; Jodie Ingles
Journal:  Circ Cardiovasc Genet       Date:  2017-08

Review 6.  Defining the Clinical Value of a Genomic Diagnosis in the Era of Next-Generation Sequencing.

Authors:  Natasha T Strande; Jonathan S Berg
Journal:  Annu Rev Genomics Hum Genet       Date:  2016-05-26       Impact factor: 8.929

7.  Yield of molecular and clinical testing for arrhythmia syndromes: report of 15 years' experience.

Authors:  Nynke Hofman; Hanno L Tan; Mariëlle Alders; Iris Kolder; Simone de Haij; Marcel M A M Mannens; Maria Paola Lombardi; Ronald H Lekanne Dit Deprez; Irene van Langen; Arthur A M Wilde
Journal:  Circulation       Date:  2013-08-20       Impact factor: 29.690

8.  Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.

Authors:  Sarah S Kalia; Kathy Adelman; Sherri J Bale; Wendy K Chung; Christine Eng; James P Evans; Gail E Herman; Sophia B Hufnagel; Teri E Klein; Bruce R Korf; Kent D McKelvey; Kelly E Ormond; C Sue Richards; Christopher N Vlangos; Michael Watson; Christa L Martin; David T Miller
Journal:  Genet Med       Date:  2016-11-17       Impact factor: 8.822

Review 9.  Hereditary Dilated Cardiomyopathy: Recent Advances in Genetic Diagnostics.

Authors:  Hyun-Young Park
Journal:  Korean Circ J       Date:  2017-02-21       Impact factor: 3.243

Review 10.  Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis.

Authors:  Jakub Sroubek; Vincent Probst; Andrea Mazzanti; Pietro Delise; Jesus Castro Hevia; Kimie Ohkubo; Alessandro Zorzi; Jean Champagne; Anna Kostopoulou; Xiaoyan Yin; Carlo Napolitano; David J Milan; Arthur Wilde; Frederic Sacher; Martin Borggrefe; Patrick T Ellinor; George Theodorakis; Isabelle Nault; Domenico Corrado; Ichiro Watanabe; Charles Antzelevitch; Giuseppe Allocca; Silvia G Priori; Steven A Lubitz
Journal:  Circulation       Date:  2016-01-21       Impact factor: 29.690

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