| Literature DB >> 2993920 |
M G Rossmann, E Arnold, J W Erickson, E A Frankenberger, J P Griffith, H J Hecht, J E Johnson, G Kamer, M Luo, A G Mosser.
Abstract
We report the first atomic resolution structure of an animal virus, human rhinovirus 14. It is strikingly similar to known icosahedral plant RNA viruses. Four neutralizing immunogenic regions have been identified. These, and corresponding antigenic sequences of polio and foot-and-mouth disease viruses, reside on external protrusions. A large cleft on each icosahedral face is probably the host cell receptor binding site.Entities:
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Year: 1985 PMID： 2993920 DOI： 10.1038/317145a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962