Literature DB >> 29937616

Investigation of organ dose variation with adult head size and pediatric age for neuro-interventional projections.

Zhenyu Xiong1, Sarath Vijayan1, Chao Guo1, Stephen Rudin1,2, Daniel R Bednarek1,2.   

Abstract

The purpose of this study was to evaluate the effect of patient head size on radiation dose to radiosensitive organs, such as the eye lens, brain and spinal cord in fluoroscopically guided neuro-interventional procedures and CBCT scans of the head. The Toshiba Infinix C-Arm System was modeled in BEAMnrc/EGSnrc Monte-Carlo code and patient organ and effective doses were calculated in DOSxynrc/EGSnrc for CBCT and interventional procedures. X-ray projections from different angles, CBCT scans, and neuro-interventional procedures were simulated on a computational head phantom for the range of head sizes in the adult population and for different pediatric ages. The difference of left-eye lens dose between the mean head size and the mean ± 1 standard deviation (SD) ranges from 20% to 300% for projection angles of 0° to 90° RAO. The differences for other organs do not vary as much and is only about 10% for the brain. For a LCI-High CBCT protocol, the difference between mean and mean ± 1 SD head size is about 100% for lens dose and only 10% for mean and peak brain dose; the difference between 20 and 3 year-old mean head size is an increase of about 200% for the eye lens dose and only 30% for mean and peak brain dose. Dose for all organs increases with decreasing head size for the same reference point air kerma. These results will allow size-specific dose estimates to be made using software such as our dose tracking system (DTS).

Entities:  

Keywords:  CBCT; EGSnrc; Monte Carlo; X-ray projection; head size; organ dose

Year:  2018        PMID: 29937616      PMCID: PMC6008644          DOI: 10.1117/12.2293958

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN: 0277-786X


  7 in total

1.  Lens of the eye dose calculation for neuro-interventional procedures and CBCT scans of the head.

Authors:  Zhenyu Xiong; Sarath Vijayan; Vijay Rana; Amit Jain; Stephen Rudin; Daniel R Bednarek
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2016-03-22

2.  Verification of the performance accuracy of a real-time skin-dose tracking system for interventional fluoroscopic procedures.

Authors:  Daniel R Bednarek; Jeffery Barbarits; Vijay K Rana; Srikanta P Nagaraja; Madhur S Josan; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2011-02-13

3.  A tracking system to calculate patient skin dose in real-time during neurointerventional procedures using a biplane x-ray imaging system.

Authors:  V K Rana; S Rudin; D R Bednarek
Journal:  Med Phys       Date:  2016-09       Impact factor: 4.071

4.  Assessment of organ and effective dose when using region-of-interest attenuators in cone-beam CT and interventional fluoroscopy.

Authors:  Zhenyu Xiong; Sarath Vijayan; Stephen Rudin; Daniel R Bednarek
Journal:  J Med Imaging (Bellingham)       Date:  2017-08-22

5.  Computerized three-dimensional segmented human anatomy.

Authors:  I G Zubal; C R Harrell; E O Smith; Z Rattner; G Gindi; P B Hoffer
Journal:  Med Phys       Date:  1994-02       Impact factor: 4.071

6.  Variation in radiation sensitivity and repair kinetics in different parts of the spinal cord.

Authors:  Magdalena Adamus-Górka; Anders Brahme; Panayiotis Mavroidis; Bengt K Lind
Journal:  Acta Oncol       Date:  2008       Impact factor: 4.089

7.  Creating a normative database of age-specific 3D geometrical data, bone density, and bone thickness of the developing skull: a pilot study.

Authors:  Hans Delye; Tim Clijmans; Maurice Yves Mommaerts; Jos Vnder Sloten; Jan Goffin
Journal:  J Neurosurg Pediatr       Date:  2015-09-04       Impact factor: 2.375

  7 in total

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