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Literature DB >> 2991600

Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide.

E A Emini, J V Hughes, D S Perlow, J Boger.

Abstract

Comparative surface feature analyses of the VP1 sequences of hepatitis A virus (HAV) and poliovirus type 1 allowed an alignment of the two sequences and an identification of probable HAV neutralization antigenic sites. A synthetic peptide containing the HAV-specific amino acid sequence of one of these sites induced anti-HAV-neutralizing antibodies. It is concluded that a structural homology exists between the two viruses, despite minimal primary sequence conservation.

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Year: 1985 PMID： 2991600 PMCID： PMC255070

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

19 in total

Review 1. Prediction of the secondary structure of proteins from their amino acid sequence.

Authors: P Y Chou; G D Fasman
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1978

2. Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection.

Authors: S Krugman; J P Giles; J Hammond
Journal: JAMA Date: 1967-05-01 Impact factor: 56.272

3. Prediction of protein antigenic determinants from amino acid sequences.

Authors: T P Hopp; K R Woods
Journal: Proc Natl Acad Sci U S A Date: 1981-06 Impact factor: 11.205

4. Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome.

Authors: V R Racaniello; D Baltimore
Journal: Proc Natl Acad Sci U S A Date: 1981-08 Impact factor: 11.205

5. Primary structure, gene organization and polypeptide expression of poliovirus RNA.

Authors: N Kitamura; B L Semler; P G Rothberg; G R Larsen; C J Adler; A J Dorner; E A Emini; R Hanecak; J J Lee; S van der Werf; C W Anderson; E Wimmer
Journal: Nature Date: 1981-06-18 Impact factor: 49.962

6. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins.

Authors: J Garnier; D J Osguthorpe; B Robson
Journal: J Mol Biol Date: 1978-03-25 Impact factor: 5.469

7. Conformation of amino acid side-chains in proteins.

Authors: J Janin; S Wodak
Journal: J Mol Biol Date: 1978-11-05 Impact factor: 5.469

8. Molecular cloning and partial sequencing of hepatitis A viral cDNA.

Authors: D L Linemeyer; J G Menke; A Martin-Gallardo; J V Hughes; A Young; S W Mitra
Journal: J Virol Date: 1985-05 Impact factor: 5.103

9. Antibodies specific for the carboxy- and amino-terminal regions of simian virus 40 large tumor antigen.

Authors: G Walter; K H Scheidtmann; A Carbone; A P Laudano; R F Doolittle
Journal: Proc Natl Acad Sci U S A Date: 1980-09 Impact factor: 11.205

10. New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates.

Authors: F T Liu; M Zinnecker; T Hamaoka; D H Katz
Journal: Biochemistry Date: 1979-02-20 Impact factor: 3.162

350 in total

10. Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil.

Authors: G Wiche; B Becker; K Luber; G Weitzer; M J Castañon; R Hauptmann; C Stratowa; M Stewart
Journal: J Cell Biol Date: 1991-07 Impact factor: 10.539

Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide.

Review 1. Prediction of the secondary structure of proteins from their amino acid sequence.

2. Infectious hepatitis. Evidence for two distinctive clinical, epidemiological, and immunological types of infection.

3. Prediction of protein antigenic determinants from amino acid sequences.

4. Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome.

5. Primary structure, gene organization and polypeptide expression of poliovirus RNA.

6. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins.

7. Conformation of amino acid side-chains in proteins.

8. Molecular cloning and partial sequencing of hepatitis A viral cDNA.

9. Antibodies specific for the carboxy- and amino-terminal regions of simian virus 40 large tumor antigen.

10. New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates.

Review 1. PROTEAN. Protein sequence analysis and prediction.

2. Comparative analysis of G1 glycoprotein-coding sequences of Cache Valley virus (Bunyaviridae: Bunyavirus) isolates.

3. BTF3 is a potential new substrate of protein kinase CK2.

4. An arginine-faced amphipathic alpha helix is required for adenovirus type 5 e4orf6 protein function.

5. A leucine-rich repeat region is conserved in pollen extensin-like (Pex) proteins in monocots and dicots.

6. High-throughput protein analysis integrating bioinformatics and experimental assays.

7. Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs.

8. Predictions of the secondary structure and antigenicity of human and bovine tropoelastins.

Review 9. Immunoinformatics: an integrated scenario.

10. Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil.