Literature DB >> 20722763

Immunoinformatics: an integrated scenario.

Namrata Tomar1, Rajat K De.   

Abstract

Genome sequencing of humans and other organisms has led to the accumulation of huge amounts of data, which include immunologically relevant data. A large volume of clinical data has been deposited in several immunological databases and as a result immunoinformatics has emerged as an important field which acts as an intersection between experimental immunology and computational approaches. It not only helps in dealing with the huge amount of data but also plays a role in defining new hypotheses related to immune responses. This article reviews classical immunology, different databases and prediction tools. It also describes applications of immunoinformatics in designing in silico vaccination and immune system modelling. All these efforts save time and reduce cost.
© 2010 The Authors. Immunology © 2010 Blackwell Publishing Ltd.

Entities:  

Mesh:

Year:  2010        PMID: 20722763      PMCID: PMC2967261          DOI: 10.1111/j.1365-2567.2010.03330.x

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  116 in total

1.  An approach to modelling in immunology.

Authors:  A Yates; C C Chan; R E Callard; A J George; J Stark
Journal:  Brief Bioinform       Date:  2001-09       Impact factor: 11.622

2.  Computer prediction of allergen proteins from sequence-derived protein structural and physicochemical properties.

Authors:  Juan Cui; Lian Yi Han; Hu Li; Choong Yong Ung; Zhi Qun Tang; Chan Juan Zheng; Zhi Wei Cao; Yu Zong Chen
Journal:  Mol Immunol       Date:  2006-03-23       Impact factor: 4.407

Review 3.  Predicting location of continuous epitopes in proteins from their primary structures.

Authors:  J L Pellequer; E Westhof; M H Van Regenmortel
Journal:  Methods Enzymol       Date:  1991       Impact factor: 1.600

4.  Induction of hepatitis A virus-neutralizing antibody by a virus-specific synthetic peptide.

Authors:  E A Emini; J V Hughes; D S Perlow; J Boger
Journal:  J Virol       Date:  1985-09       Impact factor: 5.103

5.  Epitome: database of structure-inferred antigenic epitopes.

Authors:  Avner Schlessinger; Yanay Ofran; Guy Yachdav; Burkhard Rost
Journal:  Nucleic Acids Res       Date:  2006-01-01       Impact factor: 16.971

6.  Epitope mapping using combinatorial phage-display libraries: a graph-based algorithm.

Authors:  Itay Mayrose; Tomer Shlomi; Nimrod D Rubinstein; Jonathan M Gershoni; Eytan Ruppin; Roded Sharan; Tal Pupko
Journal:  Nucleic Acids Res       Date:  2006-12-06       Impact factor: 16.971

7.  ImmTree: database of evolutionary relationships of genes and proteins in the human immune system.

Authors:  Csaba Ortutay; Markku Siermala; Mauno Vihinen
Journal:  Immunome Res       Date:  2007-03-21

8.  DyNAVacS: an integrative tool for optimized DNA vaccine design.

Authors:  Nagarajan Harish; Rekha Gupta; Parul Agarwal; Vinod Scaria; Beena Pillai
Journal:  Nucleic Acids Res       Date:  2006-07-01       Impact factor: 16.971

9.  T-Epitope Designer: A HLA-peptide binding prediction server.

Authors:  Pandjassarame Kangueane; Meena Kishore Sakharkar
Journal:  Bioinformation       Date:  2005-05-15

10.  NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11.

Authors:  Claus Lundegaard; Kasper Lamberth; Mikkel Harndahl; Søren Buus; Ole Lund; Morten Nielsen
Journal:  Nucleic Acids Res       Date:  2008-05-07       Impact factor: 16.971

View more
  37 in total

1.  In silico identification of epitopes from house cat and dog proteins as peptide immunotherapy candidates based on human leukocyte antigen binding affinity.

Authors:  H N Tipu; D Ahmed; S A H Gardezi
Journal:  Iran J Vet Res       Date:  2017       Impact factor: 1.376

2.  In-silico screening, identification and validation of a novel vaccine candidate in the fight against Plasmodium falciparum.

Authors:  Sandeep Kumar Panda; Rajani Kanta Mahapatra
Journal:  Parasitol Res       Date:  2017-02-24       Impact factor: 2.289

3.  Immunoinformatic Approaches for Vaccine Designing for Pathogens with Unclear Pathogenesis.

Authors:  Naina Arora; Anand K Keshri; Rimanpreet Kaur; Suraj Singh Rawat; Amit Prasad
Journal:  Methods Mol Biol       Date:  2022

4.  In Silico Analysis of HA2/Mx Chimera Peptide for Developing an Adjuvanted Vaccine to Induce Immune Responses Against Influenza Viruses.

Authors:  Sina Soleimani; Omid Madadgar; Shahla Shahsavandi; Homayoon Mahravani; Mohsen Lotfi
Journal:  Adv Pharm Bull       Date:  2015-12-31

Review 5.  The epitopes in wheat proteins for defining toxic units relevant to human health.

Authors:  Angéla Juhász; Gyöngyvér Gell; Frank Békés; Ervin Balázs
Journal:  Funct Integr Genomics       Date:  2012-11-20       Impact factor: 3.410

6.  Brachypodium distachyon as a model for defining the allergen potential of non-prolamin proteins.

Authors:  A Juhász; Gy Gell; E Sebestyén; R Haraszi; L Tamás; E Balázs
Journal:  Funct Integr Genomics       Date:  2012-08-30       Impact factor: 3.410

Review 7.  Biomarkers of immunotoxicity for environmental and public health research.

Authors:  Paurene Duramad; Nina T Holland
Journal:  Int J Environ Res Public Health       Date:  2011-05-06       Impact factor: 3.390

Review 8.  T-cell epitope vaccine design by immunoinformatics.

Authors:  Atanas Patronov; Irini Doytchinova
Journal:  Open Biol       Date:  2013-01-08       Impact factor: 6.411

9.  Improved method for linear B-cell epitope prediction using antigen's primary sequence.

Authors:  Harinder Singh; Hifzur Rahman Ansari; Gajendra P S Raghava
Journal:  PLoS One       Date:  2013-05-07       Impact factor: 3.240

10.  Computational and experimental validation of B and T-cell epitopes of the in vivo immune response to a novel malarial antigen.

Authors:  Elke S Bergmann-Leitner; Sidhartha Chaudhury; Nicholas J Steers; Mark Sabato; Vito Delvecchio; Anders S Wallqvist; Christian F Ockenhouse; Evelina Angov
Journal:  PLoS One       Date:  2013-08-16       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.