| Literature DB >> 2991116 |
J W Höppener, P H Steenbergh, J Zandberg, A H Geurts van Kessel, S B Baylin, B D Nelkin, H S Jansz, C J Lips.
Abstract
A second human calcitonin/calcitonin gene related peptide (hCT/CGRP) gene has been identified. This second hCT/CGRP gene has been shown to contain sequences highly homologous to exons 3, 5 (CGRP-encoding), and 6 of the first hCT/CGRP gene, but sequences closely related to exon 4 (CT-encoding) could not be demonstrated. Southern blot hybridization analysis of DNA from human-rodent somatic cell hybrids showed that the second hCT/CGRP gene is located in the q12-pter region of chromosome 11. The first hCT/CGRP gene has previously been assigned to the p13-p15 region of chromosome 11.Entities:
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Year: 1985 PMID: 2991116 DOI: 10.1007/bf00273453
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132