D Cheng1,2, L Bonato3, C Leinkram4. 1. Royal Melbourne Hospital, Parkville, Australia. davidemcheng@gmail.com. 2. , Parkville, Australia. davidemcheng@gmail.com. 3. Monash University, Melbourne, Australia. 4. Melbourne Hernia Clinic, St Kilda East, Australia.
Abstract
PURPOSE: Ventral hernias are a common surgical issue and a myriad of surgical mesh designs has been developed for their treatment. Many of these new mesh designs have not been extensively tested and their complications rates are largely unknown. The C-QUR V-Patch Mesh™ combines a unique knit construction polypropylene mesh with an omega-3 fatty acid coating. There has only previously been one reported study investigating this mesh. METHODS: A multicentre cohort study, with a single surgeon, of 168 consecutive patients with ventral hernias underwent repair using a standardized open pre-peritoneal approach with the novel C-QUR V-Patch Mesh™ between January 2013 and June 2015. A median follow-up of 37 months was completed to assess the patients for hernia infection and recurrence rates. Mesh infections were further classified into early and late infections for further subgroup analysis. RESULTS: Infection and recurrence rates of the C-QUR V-Patch® were compared with similar published results of alternate mesh designs. Surgical site infection rates were 7.7% and recurrence rates were 2.4%. The infection rate rose dramatically to 19.0% when the mesh was placed intra-peritoneally. The rate of mesh explantation was 2.4% and usually occurred between 4 and 12 months post-operatively. Smoking was the only factor that appeared to be associated with recurrence. CONCLUSION: This series finds that recurrence rates associated with the novel C-QUR V-Patch Mesh™ is acceptably low; however, infection rates appear to be higher when compared to comparable products for use in ventral hernia repairs.
PURPOSE:Ventral hernias are a common surgical issue and a myriad of surgical mesh designs has been developed for their treatment. Many of these new mesh designs have not been extensively tested and their complications rates are largely unknown. The C-QUR V-Patch Mesh™ combines a unique knit construction polypropylene mesh with an omega-3 fatty acid coating. There has only previously been one reported study investigating this mesh. METHODS: A multicentre cohort study, with a single surgeon, of 168 consecutive patients with ventral hernias underwent repair using a standardized open pre-peritoneal approach with the novel C-QUR V-Patch Mesh™ between January 2013 and June 2015. A median follow-up of 37 months was completed to assess the patients for hernia infection and recurrence rates. Mesh infections were further classified into early and late infections for further subgroup analysis. RESULTS:Infection and recurrence rates of the C-QUR V-Patch® were compared with similar published results of alternate mesh designs. Surgical site infection rates were 7.7% and recurrence rates were 2.4%. The infection rate rose dramatically to 19.0% when the mesh was placed intra-peritoneally. The rate of mesh explantation was 2.4% and usually occurred between 4 and 12 months post-operatively. Smoking was the only factor that appeared to be associated with recurrence. CONCLUSION: This series finds that recurrence rates associated with the novel C-QUR V-Patch Mesh™ is acceptably low; however, infection rates appear to be higher when compared to comparable products for use in ventral hernia repairs.
Authors: Ruth Kaufmann; Jens A Halm; Hasan H Eker; Pieter J Klitsie; Jeroen Nieuwenhuizen; Dick van Geldere; Maarten P Simons; Erwin van der Harst; Martijne van 't Riet; Bronno van der Holt; Gert Jan Kleinrensink; Johannes Jeekel; Johan F Lange Journal: Lancet Date: 2018-02-17 Impact factor: 79.321