Literature DB >> 2989105

Cloning of cDNAs coding for rat hepatic microsomal UDP-glucuronyltransferases.

M R Jackson, L R McCarthy, R B Corser, G C Barr, B Burchell.   

Abstract

Radioiodinated, affinity-purified, anti-UDP-glucuronyltransferase (UDPGT) antibodies have been used to isolate cDNAs coding for UDPGT(s) from a rat liver cDNA library cloned in the expression vector bacteriophage lambda gt11. The sizes of ten cloned cDNAs range from 0.3-2.1 kb. The identity of the cDNAs was confirmed by the hybrid-select translation and immunochemical analyses. Restriction mapping indicates that two classes of cDNA coding for different UDPGT mRNAs have been cloned.

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Year:  1985        PMID： 2989105     DOI： 10.1016/0378-1119(85)90122-2

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  5 in total

1.  Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA.

Authors:  M R Jackson; L R McCarthy; D Harding; S Wilson; M W Coughtrie; B Burchell
Journal:  Biochem J       Date:  1987-03-01       Impact factor: 3.857

Review 2.  From Classical Toxicology to Tox21: Some Critical Conceptual and Technological Advances in the Molecular Understanding of the Toxic Response Beginning From the Last Quarter of the 20th Century.

Authors:  Supratim Choudhuri; Geoffrey W Patton; Ronald F Chanderbhan; Antonia Mattia; Curtis D Klaassen
Journal:  Toxicol Sci       Date:  2018-01-01       Impact factor: 4.849

3.  The full length coding sequence of rat liver androsterone UDP-glucuronyltransferase cDNA and comparison with other members of this gene family.

Authors:  M R Jackson; B Burchell
Journal:  Nucleic Acids Res       Date:  1986-01-24       Impact factor: 16.971

4.  The use of jejunal transplants to treat a genetic enzyme deficiency.

Authors:  B M Jaffe; A A Burgos; M Martinez-Noack
Journal:  Ann Surg       Date:  1996-06       Impact factor: 12.969

Review 5.  Revisiting the Latency of Uridine Diphosphate-Glucuronosyltransferases (UGTs)-How Does the Endoplasmic Reticulum Membrane Influence Their Function?

Authors:  Yuejian Liu; Michael W H Coughtrie
Journal:  Pharmaceutics       Date:  2017-08-30       Impact factor: 6.321
  5 in total

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