Literature DB >> 2987935

Three-dimensional structure of ubiquitin at 2.8 A resolution.

S Vijay-Kumar, C E Bugg, K D Wilkinson, W J Cook.   

Abstract

The three-dimensional structure of ubiquitin has been determined at 2.8 A resolution. X-ray diffraction data for the native protein and derivatives were collected with an automated diffractometer. Phases were obtained by use of a single isomorphous mercuric acetate derivative. The molecule contains a pronounced hydrophobic core. Prominent secondary structural features include three and one-half turns of alpha-helix, a mixed beta-sheet that contains four strands, and seven reverse turns. The histidine, tyrosine, and two phenylalanine residues are located on the surface of the molecule.

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Year:  1985        PMID： 2987935      PMCID： PMC397829          DOI： 10.1073/pnas.82.11.3582

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  27 in total

1.  The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus.

Authors:  T L Low; G B Thurman; M McAdoo; J McClure; J L Rossio; P H Naylor; A L Goldstein
Journal:  J Biol Chem       Date:  1979-02-10       Impact factor: 5.157

2.  Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells.

Authors:  G Goldstein; M Scheid; U Hammerling; D H Schlesinger; H D Niall; E A Boyse
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Nuclear magnetic resonance studies of the denaturation of ubiquitin.

Authors:  R E Lenkinski; D M Chen; J D Glickson; G Goldstein
Journal:  Biochim Biophys Acta       Date:  1977-09-27

4.  Amino-terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24.

Authors:  L T Hunt; M O Dayhoff
Journal:  Biochem Biophys Res Commun       Date:  1977-01-24       Impact factor: 3.575

5.  The chemistry and biology of thymosin. II. Amino acid sequence analysis of thymosin alpha1 and polypeptide beta1.

Authors:  T L Low; A L Goldstein
Journal:  J Biol Chem       Date:  1979-02-10       Impact factor: 5.157

Review 6.  The ubiquitin-mediated proteolytic pathway and mechanisms of energy-dependent intracellular protein degradation.

Authors:  A Ciechanover; D Finley; A Varshavsky
Journal:  J Cell Biochem       Date:  1984       Impact factor: 4.429

7.  Free ubiquitin is a non-histone protein of trout testis chromatin.

Authors:  D C Watson; W B Levy; G H Dixon
Journal:  Nature       Date:  1978-11-09       Impact factor: 49.962

8.  Early stages of human marrow lymphocyte differentiation: induction in vitro by thymopoietin and ubiquitin.

Authors:  W A Kagan; F P Siegal; S Gupta; G Goldstein; R A Good
Journal:  J Immunol       Date:  1979-02       Impact factor: 5.422

9.  The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells.

Authors:  D H Schlesinger; G Goldstein; H D Niall
Journal:  Biochemistry       Date:  1975-05-20       Impact factor: 3.162

10.  Induction of human granulocyte differentiation in vitro by ubiquitin and thymopoietin.

Authors:  W A Kagan; G J O'Neill; G S Incefy; G Goldstein; R A Good
Journal:  Blood       Date:  1977-08       Impact factor: 22.113
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  25 in total

Review 1.  The ubiquitin-proteasome pathway and proteasome inhibitors.

Authors:  J Myung; K B Kim; C M Crews
Journal:  Med Res Rev       Date:  2001-07       Impact factor: 12.944

2.  Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97.

Authors:  Xuemei Yuan; Peter Simpson; Ciaran McKeown; Hisao Kondo; Keiji Uchiyama; Russell Wallis; Ingrid Dreveny; Catherine Keetch; Xiaodong Zhang; Carol Robinson; Paul Freemont; Stephen Matthews
Journal:  EMBO J       Date:  2004-03-18       Impact factor: 11.598

3.  Monoubiquitin carries a novel internalization signal that is appended to activated receptors.

Authors:  S C Shih; K E Sloper-Mould; L Hicke
Journal:  EMBO J       Date:  2000-01-17       Impact factor: 11.598

4.  Comparison of multiple Amber force fields and development of improved protein backbone parameters.

Authors:  Viktor Hornak; Robert Abel; Asim Okur; Bentley Strockbine; Adrian Roitberg; Carlos Simmerling
Journal:  Proteins       Date:  2006-11-15

5.  Wavelets and molecular structure.

Authors:  M Carson
Journal:  J Comput Aided Mol Des       Date:  1996-08       Impact factor: 3.686

6.  A "housekeeping" gene on the X chromosome encodes a protein similar to ubiquitin.

Authors:  D Toniolo; M Persico; M Alcalay
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

7.  Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin.

Authors:  R Ramage; J Green; T W Muir; O M Ogunjobi; S Love; K Shaw
Journal:  Biochem J       Date:  1994-04-01       Impact factor: 3.857

Review 8.  The Solution Assembly of Biological Molecules Using Ion Mobility Methods: From Amino Acids to Amyloid β-Protein.

Authors:  Christian Bleiholder; Michael T Bowers
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2017-03-24       Impact factor: 10.745

Review 9.  The pup-proteasome system of Mycobacterium tuberculosis.

Authors:  Marie I Samanovic; Huilin Li; K Heran Darwin
Journal:  Subcell Biochem       Date:  2013

10.  Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes.

Authors:  Anthony Gonçalves; Emmanuelle Charafe-Jauffret; François Bertucci; Stéphane Audebert; Yves Toiron; Benjamin Esterni; Florence Monville; Carole Tarpin; Jocelyne Jacquemier; Gilles Houvenaeghel; Christian Chabannon; Jean-Marc Extra; Patrice Viens; Jean-Paul Borg; Daniel Birnbaum
Journal:  Mol Cell Proteomics       Date:  2008-04-20       Impact factor: 5.911
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