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Literature DB >> 29856447

Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging.

Weijia Hou¹, Yuan Liu, Ying Jiang, Yuan Wu, Cheng Cui, Yanyue Wang, Liqin Zhang, I-Ting Teng, Weihong Tan.

Abstract

We designed an aptamer-based multifunctional ligand which, upon conjugation to the surface of upconversion nanoparticles (UCNPs), could realize phase transfer, covalent photosensitizer (PS) loading, and cancer cell targeting in one simple step. The as-built PDT nanodrug is selectively internalized into cancer cells and it exhibits highly efficient and selective cytotoxicity.

Entities: CellLine Chemical Disease Gene Species

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Year: 2018 PMID： 29856447 PMCID： PMC6472954 DOI： 10.1039/c8nr01096j

Source DB: PubMed Journal: Nanoscale ISSN： 2040-3364 Impact factor: 7.790

33 in total

Review 1. State of the art in the delivery of photosensitizers for photodynamic therapy.

Authors: Yvette Niamien Konan; Robert Gurny; Eric Allémann
Journal: J Photochem Photobiol B Date: 2002-03 Impact factor: 6.252

Review 2. Imaging and photodynamic therapy: mechanisms, monitoring, and optimization.

Authors: Jonathan P Celli; Bryan Q Spring; Imran Rizvi; Conor L Evans; Kimberley S Samkoe; Sarika Verma; Brian W Pogue; Tayyaba Hasan
Journal: Chem Rev Date: 2010-05-12 Impact factor: 60.622

3. Aptamer-target binding triggered molecular mediation of singlet oxygen generation.

Authors: Zhiwen Tang; Zhi Zhu; Prabodhika Mallikaratchy; Ronghua Yang; Kwame Sefah; Weihong Tan
Journal: Chem Asian J Date: 2010-04-01

4. Aptamers evolved from live cells as effective molecular probes for cancer study.

Authors: Dihua Shangguan; Ying Li; Zhiwen Tang; Zehui Charles Cao; Hui William Chen; Prabodhika Mallikaratchy; Kwame Sefah; Chaoyong James Yang; Weihong Tan
Journal: Proc Natl Acad Sci U S A Date: 2006-07-27 Impact factor: 11.205

5. In vitro selection of RNA molecules that bind specific ligands.

Authors: A D Ellington; J W Szostak
Journal: Nature Date: 1990-08-30 Impact factor: 49.962

6. Versatile photosensitizers for photodynamic therapy at infrared excitation.

Authors: Peng Zhang; Wim Steelant; Manoj Kumar; Matthew Scholfield
Journal: J Am Chem Soc Date: 2007-03-27 Impact factor: 15.419

Review 7. Direct tumor damage mechanisms of photodynamic therapy.

Authors: Dominika Nowis; Marcin Makowski; Tomasz Stokłosa; Magdalena Legat; Tadeusz Issat; Jakub Gołab
Journal: Acta Biochim Pol Date: 2005-06-25 Impact factor: 2.149

8. DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells.

Authors: Yanrong Wu; Kwame Sefah; Haipeng Liu; Ruowen Wang; Weihong Tan
Journal: Proc Natl Acad Sci U S A Date: 2009-12-22 Impact factor: 11.205

9. Cell-specific internalization study of an aptamer from whole cell selection.

Authors: Zeyu Xiao; Dihua Shangguan; Zehui Cao; Xiaohong Fang; Weihong Tan
Journal: Chemistry Date: 2008 Impact factor: 5.236

10. Cell-specific aptamer probes for membrane protein elucidation in cancer cells.

Authors: Dihua Shangguan; Zehui Cao; Ling Meng; Prabodhika Mallikaratchy; Kwame Sefah; Hui Wang; Ying Li; Weihong Tan
Journal: J Proteome Res Date: 2008-03-26 Impact factor: 4.466

7 in total

1. Effect of tetragonal to cubic phase transition on the upconversion luminescence properties of A/B site erbium-doped perovskite BaTiO₃.

Authors: Hyeongyu Bae; Kang Taek Lee
Journal: RSC Adv Date: 2019-01-18 Impact factor: 4.036

Aptamer-based multifunctional ligand-modified UCNPs for targeted PDT and bioimaging.

Review 1. State of the art in the delivery of photosensitizers for photodynamic therapy.

Review 2. Imaging and photodynamic therapy: mechanisms, monitoring, and optimization.

3. Aptamer-target binding triggered molecular mediation of singlet oxygen generation.

4. Aptamers evolved from live cells as effective molecular probes for cancer study.

5. In vitro selection of RNA molecules that bind specific ligands.

6. Versatile photosensitizers for photodynamic therapy at infrared excitation.

Review 7. Direct tumor damage mechanisms of photodynamic therapy.

8. DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells.

9. Cell-specific internalization study of an aptamer from whole cell selection.

10. Cell-specific aptamer probes for membrane protein elucidation in cancer cells.

1. Effect of tetragonal to cubic phase transition on the upconversion luminescence properties of A/B site erbium-doped perovskite BaTiO₃.

Review 2. Functional Polymer Nanocarriers for Photodynamic Therapy.

Review 3. Aptamer-Enabled Nanomaterials for Therapeutics, Drug Targeting and Imaging.

Review 4. Recent advances in functionalized upconversion nanoparticles for light-activated tumor therapy.

Review 5. Antitumor Applications of Photothermal Agents and Photothermal Synergistic Therapies.

Review 6. Nanomaterial based aptasensors for clinical and environmental diagnostic applications.

Review 7. Multifunctional phototheranostic nanomedicine for cancer imaging and treatment.