Literature DB >> 2982727

Chromosomal localization and preliminary characterization of the human gene encoding insulin-like growth factor II.

P de Pagter-Holthuizen, J W Höppener, M Jansen, A H Geurts van Kessel, G J van Ommen, J S Sussenbach.   

Abstract

A cDNA probe corresponding to mRNA encoding a closely related variant of human insulin-like growth factor II (IGF-II) was used for the chromosomal assignment of the IGF-II gene. Southern blot hybridization analysis of DNA from human-Chinese hamster somatic cell hybrids showed that the human IGF-II gene is located on chromosome 11. Using the same IGF-II variant probe, a cosmid was isolated which contains the human IGF-II gene. Restriction enzyme analysis revealed that the gene encoding IGF-II has a discontinuous structure and contains at least four exons.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2982727     DOI： 10.1007/bf00293291

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  21 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

Review 2.  Hormonal regulation of growth by somatomedin and other tissue growth factors.

Authors:  W H Daughaday
Journal:  Clin Endocrinol Metab       Date:  1977-03

3.  Rapid and efficient cosmid cloning.

Authors:  D Ish-Horowicz; J F Burke
Journal:  Nucleic Acids Res       Date:  1981-07-10       Impact factor: 16.971

4.  The human thyroglobulin gene contains two 15-17 kb introns near its 3'-end.

Authors:  G J van Ommen; A C Arnberg; F Baas; H Brocas; A Sterk; W H Tegelaers; G Vassart; J J de Vijlder
Journal:  Nucleic Acids Res       Date:  1983-04-25       Impact factor: 16.971

5.  Effect of growth hormone and peptide fractions containing somatomedin activity on growth and cartilage metabolism of Snell dwarfmice.

Authors:  J L Van den Brande; S van Buul-Offers
Journal:  Acta Endocrinol (Copenh)       Date:  1979-10

6.  Primary structure of human insulin-like growth factor II.

Authors:  E Rinderknecht; R E Humbel
Journal:  FEBS Lett       Date:  1978-05-15       Impact factor: 4.124

7.  Translocation of c-ab1 oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia.

Authors:  C R Bartram; A de Klein; A Hagemeijer; T van Agthoven; A Geurts van Kessel; D Bootsma; G Grosveld; M A Ferguson-Smith; T Davies; M Stone
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

8.  Purification and primary structure of a polypeptide with multiplication-stimulating activity from rat liver cell cultures. Homology with human insulin-like growth factor II.

Authors:  H Marquardt; G J Todaro; L E Henderson; S Oroszlan
Journal:  J Biol Chem       Date:  1981-07-10       Impact factor: 5.157

9.  Sequence analysis of somatomedin-C: confirmation of identity with insulin-like growth factor I.

Authors:  D G Klapper; M E Svoboda; J J Van Wyk
Journal:  Endocrinology       Date:  1983-06       Impact factor: 4.736

10.  Characterization of the Philadelphia chromosome by gene mapping.

Authors:  A H Geurts van Kessel; H ten Brinke; W A Boere; W C den Boer; P G de Groot; A Hagemeijer; P Meera Khan; P L Pearson
Journal:  Cytogenet Cell Genet       Date:  1981
View more
  5 in total

1.  Ava II RFLP at the insulin-like growth factor II (IGF II) locus on chromosome 11.

Authors:  H Schneid; F Girard; M Binoux; Y Le Bouc
Journal:  Nucleic Acids Res       Date:  1989-01-11       Impact factor: 16.971

2.  Dual role for transcription factor AP-2 in the regulation of the major fetal promoter P3 of the gene for human insulin-like growth factor II.

Authors:  L E Rietveld; A M Koonen-Reemst; J S Sussenbach; P E Holthuizen
Journal:  Biochem J       Date:  1999-03-15       Impact factor: 3.857

3.  Molecular nature of genetic changes resulting in loss of heterozygosity of chromosome 11 in Wilms' tumours.

Authors:  M Mannens; R M Slater; C Heyting; J Bliek; J de Kraker; N Coad; P de Pagter-Holthuizen; P L Pearson
Journal:  Hum Genet       Date:  1988-12       Impact factor: 4.132

4.  Isolation of the human insulin-like growth factor genes: insulin-like growth factor II and insulin genes are contiguous.

Authors:  G I Bell; D S Gerhard; N M Fong; R Sanchez-Pescador; L B Rall
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

5.  Promoter-specific expression and imprint status of marsupial IGF2.

Authors:  Jessica M Stringer; Shunsuke Suzuki; Andrew J Pask; Geoff Shaw; Marilyn B Renfree
Journal:  PLoS One       Date:  2012-07-25       Impact factor: 3.240
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.