Literature DB >> 29793762

Lnc'ing Ca2+, SERCA and cardiac disease.

Tim Vervliet1, Emma L Robinson2, H Llewelyn Roderick3.   

Abstract

Loss of SERCA function contributes to reduced contractility, Ca2+ overload and arrhythmias in the diseased heart. A long non-coding RNA (ZFAS1) upregulated in cardiac disease is reported to directly inhibit SERCA function. The implications for cardiac disease and the wider roles of SERCA are discussed.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Calcium/Ca2; Cardiac myocytes; Excitation contraction coupling/ECC; Long non coding RNA/lncRNA; SERCA

Mesh：

Substances：

Year:  2018        PMID： 29793762     DOI： 10.1016/j.ceca.2018.05.005

Source DB:  PubMed          Journal:  Cell Calcium        ISSN： 0143-4160            Impact factor:   6.817


  6 in total

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Review 2.  Noncoding RNAs in cardiovascular diseases.

Authors:  Priyatansh Gurha
Journal:  Curr Opin Cardiol       Date:  2019-05       Impact factor: 2.161

Review 3.  Calcium Signaling in Cardiomyocyte Function.

Authors:  Guillaume Gilbert; Kateryna Demydenko; Eef Dries; Rosa Doñate Puertas; Xin Jin; Karin Sipido; H Llewelyn Roderick
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-03-02       Impact factor: 10.005

Review 4.  Proarrhythmic Remodeling of Calcium Homeostasis in Cardiac Disease; Implications for Diabetes and Obesity.

Authors:  Shanna Hamilton; Dmitry Terentyev
Journal:  Front Physiol       Date:  2018-10-30       Impact factor: 4.566

5.  Downregulation of lncRNA ZFAS1 protects H9c2 cardiomyocytes from ischemia/reperfusion‑induced apoptosis via the miR‑590‑3p/NF‑κB signaling pathway.

Authors:  Peng Huang; Dongbai Yang; Lianzhi Yu; Yu Shi
Journal:  Mol Med Rep       Date:  2020-07-13       Impact factor: 2.952

6.  Inhibition of the long non-coding RNA ZFAS1 attenuates ferroptosis by sponging miR-150-5p and activates CCND2 against diabetic cardiomyopathy.

Authors:  Tingjuan Ni; Xingxiao Huang; Sunlei Pan; Zhongqiu Lu
Journal:  J Cell Mol Med       Date:  2021-10-05       Impact factor: 5.310
  6 in total

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