Literature DB >> 29770060

Setting the stage for expanding HIV pre-exposure prophylaxis use in Canada.

M Hull1,2, Dhs Tan3.   

Abstract

Human immunodeficiency virus (HIV) infection continues to disproportionately affect vulnerable populations in Canada; particularly men who have sex with men (MSM). Novel HIV prevention strategies have recently expanded from the use of non-occupational post-exposure prophylaxis (nPEP) after high risk exposures to the use of pre-exposure prophylaxis (PrEP) in which individuals reduce risk of HIV infection through use of combination antiretrovirals taken prior to risk exposure. With approval of tenofovir/emtricitabine (TDF/FTC) for use as PrEP only in early 2016, and with limited public funding to date, uptake in Canada is in its preliminary stages. These biomedical prevention strategies have proven efficacy for MSM, and they may have potential for other at-risk populations. With generic formulations of TDF/FTC now available in Canada, there is an opportunity for widespread implementation. Expanding knowledge of health care providers across Canada on how best to assess, refer for or prescribe and monitor PrEP will contribute to the current efforts to reach the global goal of eliminating new HIV infections.

Entities:  

Year:  2017        PMID: 29770060      PMCID: PMC5937069          DOI: 10.14745/ccdr.v43i12a05

Source DB:  PubMed          Journal:  Can Commun Dis Rep        ISSN: 1188-4169


  36 in total

1.  A Clinical Home for Preexposure Prophylaxis: Diverse Health Care Providers' Perspectives on the "Purview Paradox".

Authors:  Susie Hoffman; John A Guidry; Kate L Collier; Joanne E Mantell; Daria Boccher-Lattimore; Farnaz Kaighobadi; Theo G M Sandfort
Journal:  J Int Assoc Provid AIDS Care       Date:  2015-08-20

2.  HIV pre-exposure prophylaxis in men who have sex with men and transgender women: a secondary analysis of a phase 3 randomised controlled efficacy trial.

Authors:  Susan P Buchbinder; David V Glidden; Albert Y Liu; Vanessa McMahan; Juan V Guanira; Kenneth H Mayer; Pedro Goicochea; Robert M Grant
Journal:  Lancet Infect Dis       Date:  2014-03-07       Impact factor: 25.071

3.  Relative effects of antiretroviral therapy and harm reduction initiatives on HIV incidence in British Columbia, Canada, 1996-2013: a modelling study.

Authors:  Bohdan Nosyk; Xiao Zang; Jeong E Min; Emanuel Krebs; Viviane D Lima; M-J Milloy; Jean Shoveller; Rolando Barrios; P Richard Harrigan; Thomas Kerr; Evan Wood; Julio S G Montaner
Journal:  Lancet HIV       Date:  2017-03-30       Impact factor: 12.767

4.  HIV transmissions during seroconversion contribute significantly to new infections in men who have sex with men in Australia.

Authors:  Doris Chibo; Matthew Kaye; Chris Birch
Journal:  AIDS Res Hum Retroviruses       Date:  2011-09-21       Impact factor: 2.205

5.  Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.

Authors:  Michael C Thigpen; Poloko M Kebaabetswe; Lynn A Paxton; Dawn K Smith; Charles E Rose; Tebogo M Segolodi; Faith L Henderson; Sonal R Pathak; Fatma A Soud; Kata L Chillag; Rodreck Mutanhaurwa; Lovemore Ian Chirwa; Michael Kasonde; Daniel Abebe; Evans Buliva; Roman J Gvetadze; Sandra Johnson; Thom Sukalac; Vasavi T Thomas; Clyde Hart; Jeffrey A Johnson; C Kevin Malotte; Craig W Hendrix; John T Brooks
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

Review 6.  Behavioural strategies to reduce HIV transmission: how to make them work better.

Authors:  Thomas J Coates; Linda Richter; Carlos Caceres
Journal:  Lancet       Date:  2008-08-05       Impact factor: 79.321

7.  The promises and challenges of pre-exposure prophylaxis as part of the emerging paradigm of combination HIV prevention.

Authors:  Carlos F Cáceres; Florence Koechlin; Pedro Goicochea; Papa-Salif Sow; Kevin R O'Reilly; Kenneth H Mayer; Peter Godfrey-Faussett
Journal:  J Int AIDS Soc       Date:  2015-07-20       Impact factor: 5.396

8.  Increased HIV incidence in men who have sex with men despite high levels of ART-induced viral suppression: analysis of an extensively documented epidemic.

Authors:  Andrew N Phillips; Valentina Cambiano; Fumiyo Nakagawa; Alison E Brown; Fiona Lampe; Alison Rodger; Alec Miners; Jonathan Elford; Graham Hart; Anne M Johnson; Jens Lundgren; Valerie C Delpech
Journal:  PLoS One       Date:  2013-02-15       Impact factor: 3.240

9.  Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk.

Authors:  James Wilton; Taylor Kain; Shawn Fowler; Trevor A Hart; Troy Grennan; John Maxwell; Darrell Hs Tan
Journal:  J Int AIDS Soc       Date:  2016-06-03       Impact factor: 5.396

10.  Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.

Authors:  Sheena McCormack; David T Dunn; Monica Desai; David I Dolling; Mitzy Gafos; Richard Gilson; Ann K Sullivan; Amanda Clarke; Iain Reeves; Gabriel Schembri; Nicola Mackie; Christine Bowman; Charles J Lacey; Vanessa Apea; Michael Brady; Julie Fox; Stephen Taylor; Simone Antonucci; Saye H Khoo; James Rooney; Anthony Nardone; Martin Fisher; Alan McOwan; Andrew N Phillips; Anne M Johnson; Brian Gazzard; Owen N Gill
Journal:  Lancet       Date:  2015-09-09       Impact factor: 79.321

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  5 in total

1.  Can we eliminate HIV?

Authors: 
Journal:  Can Fam Physician       Date:  2018-01       Impact factor: 3.275

2.  The role of public health units in the delivery of HIV pre-exposure prophylaxis (PrEP).

Authors:  Lauren Orser; Patrick O'Byrne
Journal:  Can J Public Health       Date:  2018-10-19

3.  Transporting Subgroup Analyses of Randomized Controlled Trials for Planning Implementation of New Interventions.

Authors:  Megha L Mehrotra; Daniel Westreich; M Maria Glymour; Elvin Geng; David V Glidden
Journal:  Am J Epidemiol       Date:  2021-08-01       Impact factor: 4.897

4.  Cohort profile: l'Actuel Pre-Exposure Prophylaxis (PrEP) Cohort study in Montreal, Canada.

Authors:  Zoë R Greenwald; Mathieu Maheu-Giroux; Jason Szabo; Judith Alexia B Robin; Michel Boissonnault; Vinh-Kim Nguyen; Réjean Thomas
Journal:  BMJ Open       Date:  2019-06-27       Impact factor: 2.692

5.  Attitudes and Practices of a Sample of Nova Scotian Physicians for the Implementation of HIV Pre-Exposure Prophylaxis.

Authors:  Jad Sinno; Nicole Doria; Nicholas Cochkanoff; Matthew Numer; Heather Neyedli; Darrell Tan
Journal:  HIV AIDS (Auckl)       Date:  2021-02-05
  5 in total

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