Literature DB >> 30341481

The role of public health units in the delivery of HIV pre-exposure prophylaxis (PrEP).

Lauren Orser1, Patrick O'Byrne2.   

Abstract

Pre-exposure prophylaxis (PrEP) is an HIV prevention strategy involving the use of once daily antiretroviral medications to prevent HIV infection. Available research supports that PrEP, when used as prescribed, can prevent HIV transmission by upwards of 96%. Such findings have led to the development of research publications and guidelines supporting PrEP for individuals at high risk for HIV acquisition, such as men who have sex with men (MSM). Despite its benefit, current use of PrEP in clinical settings has been undermined by false impressions of poor efficacy of PrEP and concerns about increased risk-taking among MSM should PrEP be readily available. Furthermore, guidance for the role of public health units in PrEP access has not been well defined. While we maintain that PrEP should be available to any person who requests it, we feel that public health units should focus on those at highest risk for HIV acquisition, and, in doing so, possibly reduce local HIV rates.

Entities:  

Keywords:  HIV; Men who have sex with men; Pre-exposure prophylaxis

Mesh:

Year:  2018        PMID: 30341481      PMCID: PMC6964540          DOI: 10.17269/s41997-018-0141-7

Source DB:  PubMed          Journal:  Can J Public Health        ISSN: 0008-4263


  12 in total

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Journal:  N Engl J Med       Date:  2010-11-23       Impact factor: 91.245

4.  Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.

Authors:  Robert M Grant; Peter L Anderson; Vanessa McMahan; Albert Liu; K Rivet Amico; Megha Mehrotra; Sybil Hosek; Carlos Mosquera; Martin Casapia; Orlando Montoya; Susan Buchbinder; Valdilea G Veloso; Kenneth Mayer; Suwat Chariyalertsak; Linda-Gail Bekker; Esper G Kallas; Mauro Schechter; Juan Guanira; Lane Bushman; David N Burns; James F Rooney; David V Glidden
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Authors:  Darrell H S Tan; Mark W Hull; Deborah Yoong; Cécile Tremblay; Patrick O'Byrne; Réjean Thomas; Julie Kille; Jean-Guy Baril; Joseph Cox; Pierre Giguere; Marianne Harris; Christine Hughes; Paul MacPherson; Shannon O'Donnell; Joss Reimer; Ameeta Singh; Lisa Barrett; Isaac Bogoch; Jody Jollimore; Gilles Lambert; Bertrand Lebouche; Gila Metz; Tim Rogers; Stephen Shafran
Journal:  CMAJ       Date:  2017-11-27       Impact factor: 8.262

6.  Willingness to Take PrEP and Potential for Risk Compensation Among Highly Sexually Active Gay and Bisexual Men.

Authors:  Christian Grov; Thomas H F Whitfield; H Jonathon Rendina; Ana Ventuneac; Jeffrey T Parsons
Journal:  AIDS Behav       Date:  2015-12

7.  Sexual risk behavior among HIV-uninfected men who have sex with men participating in a tenofovir preexposure prophylaxis randomized trial in the United States.

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Journal:  J Acquir Immune Defic Syndr       Date:  2013-09-01       Impact factor: 3.731

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Authors:  David I Dolling; Monica Desai; Alan McOwan; Richard Gilson; Amanda Clarke; Martin Fisher; Gabriel Schembri; Ann K Sullivan; Nicola Mackie; Iain Reeves; Mags Portman; John Saunders; Julie Fox; Jake Bayley; Michael Brady; Christine Bowman; Charles J Lacey; Stephen Taylor; David White; Simone Antonucci; Mitzy Gafos; Sheena McCormack; Owen N Gill; David T Dunn; Anthony Nardone
Journal:  Trials       Date:  2016-03-24       Impact factor: 2.279

Review 9.  Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here?

Authors:  Myron S Cohen; M Kumi Smith; Kathryn E Muessig; Timothy B Hallett; Kimberly A Powers; Angela D Kashuba
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10.  Gonorrhea in Canada, 2010-2015.

Authors:  Y Choudhri; J Miller; J Sandhu; A Leon; J Aho
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  4 in total

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Authors:  Patrick OʼByrne; Paul MacPherson; Lauren Orser; Jean Daniel Jacob; Dave Holmes
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3.  Active-Offer Nurse-Led PrEP (PrEP-RN) Referrals: Analysis of Uptake Rates and Reasons for Declining.

Authors:  Patrick O'Byrne; Lauren Orser; Marlene Haines
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4.  Pre-exposure prophylaxis makes it possible to better live one's sexuality and guide men who have sex with men towards a responsible approach to their health: a phenomenological qualitative study about primary motivations for PrEP.

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