| Literature DB >> 29766399 |
Patrycja Nowak-Sliwinska1,2, Kari Alitalo3, Elizabeth Allen4, Andrey Anisimov3, Alfred C Aplin5, Robert Auerbach6, Hellmut G Augustin7,8,9, David O Bates10, Judy R van Beijnum11, R Hugh F Bender12, Gabriele Bergers4,13, Andreas Bikfalvi14, Joyce Bischoff15, Barbara C Böck7,8,9, Peter C Brooks16, Federico Bussolino17,18, Bertan Cakir19, Peter Carmeliet20,21, Daniel Castranova22, Anca M Cimpean23, Ondine Cleaver24, George Coukos25, George E Davis26, Michele De Palma27, Anna Dimberg28, Ruud P M Dings29, Valentin Djonov30, Andrew C Dudley31,32, Neil P Dufton33, Sarah-Maria Fendt34,35, Napoleone Ferrara36, Marcus Fruttiger37, Dai Fukumura38, Bart Ghesquière39,40, Yan Gong19, Robert J Griffin29, Adrian L Harris41, Christopher C W Hughes12, Nan W Hultgren12, M Luisa Iruela-Arispe42, Melita Irving25, Rakesh K Jain38, Raghu Kalluri43, Joanna Kalucka20,21, Robert S Kerbel44, Jan Kitajewski45, Ingeborg Klaassen46, Hynda K Kleinmann47, Pieter Koolwijk48, Elisabeth Kuczynski44, Brenda R Kwak49, Koen Marien50, Juan M Melero-Martin51, Lance L Munn38, Roberto F Nicosia5,52, Agnes Noel53, Jussi Nurro54, Anna-Karin Olsson55, Tatiana V Petrova56, Kristian Pietras57, Roberto Pili58, Jeffrey W Pollard59, Mark J Post60, Paul H A Quax61, Gabriel A Rabinovich62, Marius Raica23, Anna M Randi33, Domenico Ribatti63,64, Curzio Ruegg65, Reinier O Schlingemann46,48, Stefan Schulte-Merker66, Lois E H Smith19, Jonathan W Song67,68, Steven A Stacker69, Jimmy Stalin66, Amber N Stratman22, Maureen Van de Velde53, Victor W M van Hinsbergh48, Peter B Vermeulen50,70, Johannes Waltenberger71, Brant M Weinstein22, Hong Xin36, Bahar Yetkin-Arik46, Seppo Yla-Herttuala54, Mervin C Yoder72, Arjan W Griffioen73.
Abstract
The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.Keywords: Angiogenesis; Aortic ring; Chorioallantoic membrane (CAM); Corneal angiogenesis; Endothelial cell migration; Hindlimb ischemia; Intussusceptive angiogenesis; Microfluidic; Myocardial angiogenesis; Plug assay; Proliferation; Recombinant proteins; Retinal vasculature; Tip cells; Vascular network; Vessel co-option; Zebrafish
Mesh：
Year: 2018 PMID： 29766399 PMCID： PMC6237663 DOI： 10.1007/s10456-018-9613-x
Source DB: PubMed Journal: Angiogenesis ISSN： 0969-6970 Impact factor: 9.596