Literature DB >> 29754567

Primary care physician experiences with integrated pharmacogenomic testing in a community health system.

Amy A Lemke1, Christina G Hutten Selkirk1, Nicole S Glaser1, Annette W Sereika1, Dyson T Wake1, Peter J Hulick1, Henry M Dunnenberger1.   

Abstract

AIM: To explore primary care physicians' views of the utility and delivery of direct access to pharmacogenomics (PGx) testing in a community health system.
METHODS: This descriptive study assessed the perspectives of 15 healthcare providers utilizing qualitative individual interviews.
RESULTS: Three main themes emerged: perceived value and utility of PGx testing; challenges to implementation in practice; and provider as well as patient needs.
CONCLUSION: While providers in this study viewed benefits of PGx testing as avoiding side effects, titrating doses more quickly, improving shared decision-making and providing psychological reassurance, challenges will need to be addressed such as privacy concerns, cost, insurance coverage and understanding the complexity of PGx test results.

Entities:  

Keywords:  clinical implementation; clinical utility; personalized medicine; pharmacogenetics; pharmacogenomic testing; pharmacogenomics; primary care physicians; qualitative research

Mesh:

Year:  2017        PMID: 29754567     DOI: 10.2217/pme-2017-0036

Source DB:  PubMed          Journal:  Per Med        ISSN: 1741-0541            Impact factor:   2.512


  18 in total

1.  Implementation and obstacles of pharmacogenetics in clinical practice: An international survey.

Authors:  Elizabeth Abou Diwan; Ralph I Zeitoun; Lea Abou Haidar; Ingolf Cascorbi; Nathalie Khoueiry Zgheib
Journal:  Br J Clin Pharmacol       Date:  2019-07-07       Impact factor: 4.335

2.  A blockchain-based framework to support pharmacogenetic data sharing.

Authors:  F Albalwy; J H McDermott; W G Newman; A Brass; A Davies
Journal:  Pharmacogenomics J       Date:  2022-07-22       Impact factor: 3.245

3.  Understanding the barriers and enablers of pharmacogenomic testing in primary care: a qualitative systematic review with meta-aggregation synthesis.

Authors:  Sadaf Qureshi; Asam Latif; Laura Condon; Ralph K Akyea; Joe Kai; Nadeem Qureshi
Journal:  Pharmacogenomics       Date:  2021-12-16       Impact factor: 2.638

4.  A stepwise approach to implementing pharmacogenetic testing in the primary care setting.

Authors:  Kristin Wiisanen Weitzel; Benjamin Q Duong; Meghan J Arwood; Aniwaa Owusu-Obeng; Noura S Abul-Husn; Barbara A Bernhardt; Brian Decker; Joshua C Denny; Eric Dietrich; John Gums; Ebony B Madden; Toni I Pollin; Rebekah Ryanne Wu; Susanne B Haga; Carol R Horowitz
Journal:  Pharmacogenomics       Date:  2019-10       Impact factor: 2.533

5.  Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene-drug pairs across ambulatory care settings.

Authors:  Emily J Cicali; Kristin Wiisanen Weitzel; Amanda R Elsey; Frank A Orlando; Michelle Vinson; Scott Mosley; D Max Smith; Richard Davis; Lori Drum; David Estores; James P Franciosi; Melanie Gross Hagen; Gabriel J Jerkins; Elvira S Mercado; Jaison Nainaparampil; Adaixa Padron; Eric I Rosenberg; Ashleigh Wright; Siegfried O Schmidt; Carol A Mathews; Larisa H Cavallari; Julie A Johnson
Journal:  Genet Med       Date:  2019-03-30       Impact factor: 8.822

6.  Adolescent perceptions of pharmacogenetic testing.

Authors:  Stephani L Stancil; Courtney Berrios; Susan Abdel-Rahman
Journal:  Pharmacogenomics       Date:  2021-04-14       Impact factor: 2.533

7.  Providers' perspectives on the clinical utility of pharmacogenomic testing in pediatric patients.

Authors:  Ina Liko; Yee Ming Lee; Danielle L Stutzman; Allison B Blackmer; Kimberly M Deininger; Ann M Reynolds; Christina L Aquilante
Journal:  Pharmacogenomics       Date:  2021-03-04       Impact factor: 2.533

8.  Approaches to assessing the provider experience with clinical pharmacogenomic information: a scoping review.

Authors:  Nicholas J Keeling; Tyler J Dunn; John P Bentley; Sujith Ramachandran; James M Hoffman; Meagen Rosenthal
Journal:  Genet Med       Date:  2021-04-29       Impact factor: 8.822

Review 9.  Pharmacogenomic Clinical Decision Support: A Review, How-to Guide, and Future Vision.

Authors:  Dyson T Wake; D Max Smith; Sadaf Kazi; Henry M Dunnenberger
Journal:  Clin Pharmacol Ther       Date:  2021-08-29       Impact factor: 6.903

10.  Qualitative user evaluation of a revised pharmacogenetic educational toolkit.

Authors:  Rachel Mills; Susanne B Haga
Journal:  Pharmgenomics Pers Med       Date:  2018-09-04
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