| Literature DB >> 29749673 |
Petra Schwille1, Joachim Spatz2, Katharina Landfester3, Eberhard Bodenschatz4, Stephan Herminghaus4, Victor Sourjik5, Tobias J Erb5, Philippe Bastiaens6, Reinhard Lipowsky7, Anthony Hyman8, Peter Dabrock9, Jean-Christophe Baret10, Tanja Vidakovic-Koch11, Peter Bieling6, Rumiana Dimova7, Hannes Mutschler1, Tom Robinson7, T-Y Dora Tang8, Seraphine Wegner3, Kai Sundmacher11.
Abstract
A large German research consortium mainly within the Max Planck Society ("MaxSynBio") was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom-up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non-living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology.Keywords: biotechnology; bottom-up design; microfluidics; protocells; synthetic biology
Year: 2018 PMID： 29749673 DOI： 10.1002/anie.201802288
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336