F Pacini1, F Basolo2, R Bellantone3, G Boni4, M A Cannizzaro5, M De Palma6, C Durante7, R Elisei8, G Fadda9, A Frasoldati10, L Fugazzola11,12, R Guglielmi13, C P Lombardi3, P Miccoli2, E Papini13, G Pellegriti14, L Pezzullo15, A Pontecorvi16, M Salvatori17, E Seregni18, P Vitti8. 1. Department of Medical, Surgical and Neurological Sciences, University of Siena, 53100, Siena, Italy. pacini8@unisi.it. 2. Department of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy. 3. U.O.C. Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy. 4. Regional Center of Nuclear Medicine, University of Pisa, Pisa, Italy. 5. Department of Medical and Surgical Sciences, Advanced Technologies "G.F.Ingrassia", University of Catania, Catania, Italy. 6. Dipartimento Chirurgico Generale e Polispecialistico Chirurgia 2, AORN Cardarelli, Naples, Italy. 7. Department of Internal Medicine and Medical Specialties, University of Rome Sapienza, Rome, Italy. 8. Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. 9. Institute of Pathology, Catholic University of the Sacred Heart, Rome, Italy. 10. Endocrinology Unit, Arcispedale S. Maria Nuova-IRCCS, Reggio Emilia, Italy. 11. Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy. 12. Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. 13. Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy. 14. Endocrinology, Department of Clinical and Experimental Medicine, University of Catania, Garibaldi-Nesima Medical Center, Catania, Italy. 15. Thyroid and Parathyroid Surgery Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori-IRCCS 'Fondazione G. Pascale', Naples, Italy. 16. Cattedra di Endocrinologia, Area di Endocrinologia e Malattie Metaboliche, Università Cattolica del Sacro Cuore, Rome, Italy. 17. Istituto di Medicina Nucleare, Policlinico Gemelli, Rome, Italy. 18. Struttura di Terapia Medico Nucleare ed Endocrinologia U.O. Medicina Nucleare Fondazione IRCCS Istituto Nazionale dei Tumori Milano, Milan, Italy.
Abstract
BACKGROUND: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. METHODS: Six scientific Italian societies entitled to cure thyroid cancer patients (the Italian Thyroid Association, the Medical Endocrinology Association, the Italian Society of Endocrinology, the Italian Association of Nuclear Medicine and Molecular Imaging, the Italian Society of Unified Endocrine Surgery and the Italian Society of Anatomic Pathology and Diagnostic Cytology) felt the need to develop a consensus report based on significant scientific advances occurred in the field. OBJECTIVE: The document includes recommendations regarding initial evaluation of thyroid nodules, clinical and ultrasound criteria for fine-needle aspiration biopsy, initial management of thyroid cancer including staging and risk assessment, surgical management, radioiodine remnant ablation, and levothyroxine therapy, short-term and long-term follow-up strategies, and management of recurrent and metastatic disease. The objective of this consensus is to inform clinicians, patients, researchers, and health policy makers about the best strategies (and their limitations) relating to the diagnosis and treatment of differentiated thyroid cancer.
BACKGROUND: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. METHODS: Six scientific Italian societies entitled to cure thyroid cancerpatients (the Italian Thyroid Association, the Medical Endocrinology Association, the Italian Society of Endocrinology, the Italian Association of Nuclear Medicine and Molecular Imaging, the Italian Society of Unified Endocrine Surgery and the Italian Society of Anatomic Pathology and Diagnostic Cytology) felt the need to develop a consensus report based on significant scientific advances occurred in the field. OBJECTIVE: The document includes recommendations regarding initial evaluation of thyroid nodules, clinical and ultrasound criteria for fine-needle aspiration biopsy, initial management of thyroid cancer including staging and risk assessment, surgical management, radioiodine remnant ablation, and levothyroxine therapy, short-term and long-term follow-up strategies, and management of recurrent and metastatic disease. The objective of this consensus is to inform clinicians, patients, researchers, and health policy makers about the best strategies (and their limitations) relating to the diagnosis and treatment of differentiated thyroid cancer.
Entities:
Keywords:
Radioiodine; Thyroid cancer; Thyroid nodules; Thyroid surgery
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