Literature DB >> 29711867

On the Mechanism of Long-Range Electron Transfer through DNA.

Bernd Giese1, Stephan Wessely1, Martin Spormann1, Ute Lindemann1, Eric Meggers1, Maria E Michel-Beyerle2.   

Abstract

Hopping between bases of similar redox potentials is the mechanism by which charge transport occurs through DNA. This was shown by rate measurements performed with double strands 1-3. This mechanism explains why hole transfer displays a strong sequence dependence, and postulates that electron transfer in unperturbed DNA should not be dependent on the sequence. © 1999 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Keywords:  Bioorganic chemistry; DNA oxidation; Electron transfer; Radicals

Year:  1999        PMID： 29711867     DOI： 10.1002/(SICI)1521-3773(19990401)38:7<996::AID-ANIE996>3.0.CO;2-4

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  5 in total

1.  Free radical yields in crystalline DNA X-irradiated at 4 K.

Authors:  M G Debije; W A Bernhard
Journal:  Radiat Res       Date:  1999-12       Impact factor: 2.841

2.  DNA Responds to Ionizing Radiation as an Insulator, Not as a "Molecular Wire"

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  1999-09       Impact factor: 15.336

3.  Mechanisms of strand break formation in DNA due to the direct effect of ionizing radiation: the dependency of free base release on the length of alternating CG oligodeoxynucleotides.

Authors:  Kiran K Sharma; Yuriy Razskazovskiy; Shubhadeep Purkayastha; William A Bernhard
Journal:  J Phys Chem B       Date:  2009-06-11       Impact factor: 2.991

4.  Charge equilibration between two distinct sites in double helical DNA.

Authors:  Sarah Delaney; Jae Yoo; Eric D A Stemp; Jacqueline K Barton
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-09       Impact factor: 11.205

5.  DNA Electrochemistry: Charge-Transport Pathways through DNA Films on Gold.

Authors:  Adela Nano; Ariel L Furst; Michael G Hill; Jacqueline K Barton
Journal:  J Am Chem Soc       Date:  2021-07-26       Impact factor: 16.383
  5 in total

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