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Literature DB >> 29698834

Role of lncRNAs in ovarian cancer: defining new biomarkers for therapeutic purposes.

Manish K Tripathi¹, Kyle Doxtater², Fatemeh Keramatnia², Chidi Zacheaus², Murali M Yallapu², Meena Jaggi², Subhash C Chauhan³.

Abstract

Long noncoding RNAs (lncRNAs) are a class of noncoding RNA, involved in regulation of diverse physiological and pathological processes. Ovarian cancer is the leading cause of death among all gynecological malignancies in the world and its underlying mechanism is still unclear. LncRNAs exhibit multiple biological functions in various stages of ovarian cancer development. We will discuss and summarize the new and important lncRNAs and their involvement in disease, which might represent promising therapeutic targets. Therapeutic intervention based on silencing or functional inhibition of target lncRNAs will be beneficial for ovarian cancer patients. Published by Elsevier Ltd.

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Year: 2018 PMID： 29698834 PMCID： PMC6139057 DOI： 10.1016/j.drudis.2018.04.010

Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851

64 in total

1. Promoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer.

Authors: Xiujie Sheng; Jianqi Li; Lei Yang; Zhiyi Chen; Qin Zhao; Linyu Tan; Yanqing Zhou; Juan Li
Journal: Oncol Rep Date: 2014-05-22 Impact factor: 3.906

2. Downregulation of BC200 in ovarian cancer contributes to cancer cell proliferation and chemoresistance to carboplatin.

Authors: D I Wu; Tianzhen Wang; Chengcheng Ren; Lei Liu; Dan Kong; Xiaoming Jin; Xiaobo Li; Guangmei Zhang
Journal: Oncol Lett Date: 2015-12-01 Impact factor: 2.967

3. LncRNA-HOST2 regulates cell biological behaviors in epithelial ovarian cancer through a mechanism involving microRNA let-7b.

Authors: Yuan Gao; Hao Meng; Shupeng Liu; Jingjing Hu; Yemin Zhang; Tingting Jiao; Yujie Liu; Jun Ou; Dan Wang; Lin Yao; Shanrong Liu; Ning Hui
Journal: Hum Mol Genet Date: 2014-10-06 Impact factor: 6.150

4. Long non-coding RNA growth arrest-specific transcript 5 is involved in ovarian cancer cell apoptosis through the mitochondria-mediated apoptosis pathway.

Authors: Jiayin Gao; Meimei Liu; Yiting Zou; Min Mao; Tingting Shen; Chen Zhang; Shasha Song; Meiling Sun; Song Zhang; Beidi Wang; Daling Zhu; Peiling Li
Journal: Oncol Rep Date: 2015-12 Impact factor: 3.906

Review 5. FIGO's staging classification for cancer of the ovary, fallopian tube, and peritoneum: abridged republication.

Authors: Jaime Prat
Journal: J Gynecol Oncol Date: 2015-04 Impact factor: 4.401

6. Long noncoding RNA C17orf91 is a potential prognostic marker and functions as an oncogene in ovarian cancer.

Authors: Jun Li; Hailin Yu; Meili Xi; Xin Lu
Journal: J Ovarian Res Date: 2016-08-17 Impact factor: 4.234

Review 7. An overview of long non-coding RNAs in ovarian cancers.

Authors: Matthieu Meryet-Figuière; Bernard Lambert; Pascal Gauduchon; Nicolas Vigneron; Emilie Brotin; Laurent Poulain; Christophe Denoyelle
Journal: Oncotarget Date: 2016-07-12

8. LncRNA NEAT1 contributes to paclitaxel resistance of ovarian cancer cells by regulating ZEB1 expression via miR-194.

Authors: Jihong An; Weiling Lv; Yongzhou Zhang
Journal: Onco Targets Ther Date: 2017-11-10 Impact factor: 4.147

9. HuR-regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancer.

Authors: Yiqing Chai; Jie Liu; Zhikun Zhang; Liwei Liu
Journal: Cancer Med Date: 2016-04-14 Impact factor: 4.452

10. Plasma long non-coding RNA MALAT1 is associated with distant metastasis in patients with epithelial ovarian cancer.

Authors: Qingjuan Chen; Yongyong Su; Xiaopeng He; Weian Zhao; Caixia Wu; Weibo Zhang; Xiaomin Si; Bingwei Dong; Lianying Zhao; Yufang Gao; Xiaowen Yang; Jianhui Chen; Jian Lu; Ximin Qiao; Yuchen Zhang
Journal: Oncol Lett Date: 2016-06-29 Impact factor: 2.967

39 in total

1. D-lnc: a comprehensive database and analytical platform to dissect the modification of drugs on lncRNA expression.

Authors: Wei Jiang; Yinwei Qu; Qian Yang; Xueyan Ma; Qianqian Meng; Juan Xu; Xinyi Liu; Shuyuan Wang
Journal: RNA Biol Date: 2019-08-07 Impact factor: 4.652

2. The role of long non-coding RNAs in mediating chemoresistance by modulating autophagy in cancer.

Authors: Ke-Tao Jin; Ze-Bei Lu; Jie-Qing Lv; Jun-Gang Zhang
Journal: RNA Biol Date: 2020-03-15 Impact factor: 4.652

3. Long Non-coding RNA BACE1-AS May Serve as an Alzheimer's Disease Blood-Based Biomarker.

Authors: Seyedeh Nahid Fotuhi; Mohammad Khalaj-Kondori; Mohammad Ali Hoseinpour Feizi; Mahnaz Talebi
Journal: J Mol Neurosci Date: 2019-07-01 Impact factor: 3.444

Review 4. New approaches in ovarian cancer based on genetics and carcinogenesis hypotheses (Review).

Authors: Raluca Ana-Maria Mogos; Razvan Popovici; Adina Elena Tanase; Tudor Calistru; Paula Popovici; Mihaela Grigore; Alexandru Carauleanu
Journal: Exp Ther Med Date: 2022-05-04 Impact factor: 2.751

5. Expression and clinical significance of lncRNA BC041954 in ovarian cancer.

Authors: Yan-Ming Lu; Ya-Ru Guo; Meng-Ya Zhou; Yue Wang
Journal: Exp Ther Med Date: 2022-04-26 Impact factor: 2.751

6. LncRNA HOXC-AS3 Suppresses the Formation of Mature miR-96 in Ovarian Cancer Cells to Promote Cell Proliferation.

Authors: Bo Yang; Li Sun; Lei Liang
Journal: Reprod Sci Date: 2021-03-02 Impact factor: 3.060

7. Propofol inhibits proliferation, migration, invasion and promotes apoptosis by regulating HOST2/JAK2/STAT3 signaling pathway in ovarian cancer cells.

Authors: Xiang Shen; Diaolan Wang; Xu Chen; Jun Peng
Journal: Cytotechnology Date: 2021-03-24 Impact factor: 2.058