| Literature DB >> 2969829 |
M F Carlier1, D Pantaloni, J A Evans, P K Lambooy, E D Korn, M R Webb.
Abstract
The hydrolysis of ATP that accompanies the polymerization of actin occurs on the F-actin subsequent to the addition of the G-ATP-actin subunit to the elongating filament. We now show that this ATP hydrolysis is essentially irreversible. Thus, a large decrease in free energy occurs at the cleavage step, F-ATP-actin----F-ADP-Pi-actin.Entities:
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Year: 1988 PMID: 2969829 DOI: 10.1016/0014-5793(88)81264-x
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124