Literature DB >> 2969829

The hydrolysis of ATP that accompanies actin polymerization is essentially irreversible.

M F Carlier1, D Pantaloni, J A Evans, P K Lambooy, E D Korn, M R Webb.   

Abstract

The hydrolysis of ATP that accompanies the polymerization of actin occurs on the F-actin subsequent to the addition of the G-ATP-actin subunit to the elongating filament. We now show that this ATP hydrolysis is essentially irreversible. Thus, a large decrease in free energy occurs at the cleavage step, F-ATP-actin----F-ADP-Pi-actin.

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Year:  1988        PMID: 2969829     DOI: 10.1016/0014-5793(88)81264-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  15 in total

1.  Actin modifies Ca2+ block of epithelial Na+ channels in planar lipid bilayers.

Authors:  B K Berdiev; R Latorre; D J Benos; I I Ismailov
Journal:  Biophys J       Date:  2001-05       Impact factor: 4.033

2.  The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

Authors:  P J Goldschmidt-Clermont; M I Furman; D Wachsstock; D Safer; V T Nachmias; T D Pollard
Journal:  Mol Biol Cell       Date:  1992-09       Impact factor: 4.138

3.  The effects of filament aging and annealing on a model lamellipodium undergoing disassembly by severing.

Authors:  P J Michalski; A E Carlsson
Journal:  Phys Biol       Date:  2010-05-26       Impact factor: 2.583

4.  Actin polymerization kinetics, cap structure, and fluctuations.

Authors:  Dimitrios Vavylonis; Qingbo Yang; Ben O'Shaughnessy
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-06       Impact factor: 11.205

5.  Polymerization kinetics of ADP- and ADP-Pi-actin determined by fluorescence microscopy.

Authors:  Ikuko Fujiwara; Dimitrios Vavylonis; Thomas D Pollard
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-15       Impact factor: 11.205

6.  Insights into the Cooperative Nature of ATP Hydrolysis in Actin Filaments.

Authors:  Harshwardhan H Katkar; Aram Davtyan; Aleksander E P Durumeric; Glen M Hocky; Anthony C Schramm; Enrique M De La Cruz; Gregory A Voth
Journal:  Biophys J       Date:  2018-09-01       Impact factor: 4.033

Review 7.  Nuclear actin: ancient clue to evolution in eukaryotes?

Authors:  Csaba Bajusz; Péter Borkúti; Ildikó Kristó; Zoltán Kovács; Csilla Abonyi; Péter Vilmos
Journal:  Histochem Cell Biol       Date:  2018-07-17       Impact factor: 4.304

8.  INF2-mediated severing through actin filament encirclement and disruption.

Authors:  Pinar S Gurel; Peng Ge; Elena E Grintsevich; Rui Shu; Laurent Blanchoin; Z Hong Zhou; Emil Reisler; Henry N Higgs
Journal:  Curr Biol       Date:  2014-01-09       Impact factor: 10.834

9.  Assembly and turnover of short actin filaments by the formin INF2 and profilin.

Authors:  Pinar S Gurel; Mu A; Bingqian Guo; Rui Shu; Dale F Mierke; Henry N Higgs
Journal:  J Biol Chem       Date:  2015-06-29       Impact factor: 5.157

10.  Exogenous adenosine triphosphate (ATP) preserves proximal tubule microfilament structure and function in vivo in a maleic acid model of ATP depletion.

Authors:  P S Kellerman
Journal:  J Clin Invest       Date:  1993-10       Impact factor: 14.808

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