Literature DB >> 29691155

Interfacial bioconjugation on emulsion droplet for biosensors.

Qifan Zhang1, Anita Scigliano2, Tarita Biver2, Andrea Pucci2, Timothy M Swager3.   

Abstract

Interfacial bioconjugation methods are developed for intact liquid emulsion droplets. Complex emulsion droplets having internal hydrocarbon and fluorocarbon immiscible structured phases maintain a dynamic interface for controlled interfacial reactivity. The internal morphological change after binding to biomolecules is readily visualized and detected by light transmission, which provides a platform for the formation of inexpensive and portable bio-sensing assays for enzymes, antibodies, nucleic acids and carbohydrates.
Copyright © 2018. Published by Elsevier Ltd.

Entities:  

Keywords:  Bioconjugation; Biosensors; Emulsions; Interfacial functionalization; Janus particles

Mesh:

Substances:

Year:  2018        PMID: 29691155      PMCID: PMC7251934          DOI: 10.1016/j.bmc.2018.04.020

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  12 in total

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