Literature DB >> 29685851

Does This Schlank Make Me Look Fat?

Bhagirath Chaurasia1, William L Holland1, Scott A Summers2.   

Abstract

Chaurasia and colleagues discuss the provocative new finding that some enzymes in the de novo sphingolipid synthesis pathway have dual roles as transcriptional regulators.
Copyright © 2018 Elsevier Ltd. All rights reserved.

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Year:  2018        PMID： 29685851      PMCID： PMC6098725          DOI： 10.1016/j.tem.2018.04.003

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  11 in total

Review 1.  Ceramide synthases as potential targets for therapeutic intervention in human diseases.

Authors:  Joo-Won Park; Woo-Jae Park; Anthony H Futerman
Journal:  Biochim Biophys Acta       Date:  2013-09-08

Review 2.  Could Ceramides Become the New Cholesterol?

Authors:  Scott A Summers
Journal:  Cell Metab       Date:  2018-01-04       Impact factor: 27.287

3.  Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements.

Authors:  Mariangela Sociale; Anna-Lena Wulf; Bernadette Breiden; Kathrin Klee; Melanie Thielisch; Franka Eckardt; Julia Sellin; Margret H Bülow; Sinah Löbbert; Nadine Weinstock; André Voelzmann; Joachim Schultze; Konrad Sandhoff; Reinhard Bauer
Journal:  Cell Rep       Date:  2018-01-28       Impact factor: 9.423

4.  A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.

Authors:  Yael Pewzner-Jung; Hyejung Park; Elad L Laviad; Liana C Silva; Sujoy Lahiri; Johnny Stiban; Racheli Erez-Roman; Britta Brügger; Timo Sachsenheimer; Felix Wieland; Manuel Prieto; Alfred H Merrill; Anthony H Futerman
Journal:  J Biol Chem       Date:  2010-01-28       Impact factor: 5.157

5.  A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy.

Authors:  Yael Pewzner-Jung; Ori Brenner; Svantje Braun; Elad L Laviad; Shifra Ben-Dor; Ester Feldmesser; Shirley Horn-Saban; Daniela Amann-Zalcenstein; Calanit Raanan; Tamara Berkutzki; Racheli Erez-Roman; Oshrit Ben-David; Michal Levy; Dorin Holzman; Hyejung Park; Abraham Nyska; Alfred H Merrill; Anthony H Futerman
Journal:  J Biol Chem       Date:  2010-01-28       Impact factor: 5.157

6.  Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism.

Authors:  Bhagirath Chaurasia; Vincent Andre Kaddai; Graeme Iain Lancaster; Darren C Henstridge; Sandhya Sriram; Dwight Lark Anolin Galam; Venkatesh Gopalan; K N Bhanu Prakash; S Sendhil Velan; Sarada Bulchand; Teh Jing Tsong; Mei Wang; Monowarul Mobin Siddique; Guan Yuguang; Kristmundur Sigmundsson; Natalie A Mellet; Jacquelyn M Weir; Peter J Meikle; M Shabeer Bin M Yassin; Asim Shabbir; James A Shayman; Yoshio Hirabayashi; Sue-Anne Toh Ee Shiow; Shigeki Sugii; Scott A Summers
Journal:  Cell Metab       Date:  2016-11-03       Impact factor: 27.287

7.  CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance.

Authors:  Suryaprakash Raichur; Siew Tein Wang; Puck Wee Chan; Ying Li; Jianhong Ching; Bhagirath Chaurasia; Bghagirath Chaurasia; Shaillay Dogra; Miina K Öhman; Kosuke Takeda; Shigeki Sugii; Yael Pewzner-Jung; Anthony H Futerman; Scott A Summers
Journal:  Cell Metab       Date:  2014-10-07       Impact factor: 27.287

8.  Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance.

Authors:  Sarah M Turpin; Hayley T Nicholls; Diana M Willmes; Arnaud Mourier; Susanne Brodesser; Claudia M Wunderlich; Jan Mauer; Elaine Xu; Philipp Hammerschmidt; Hella S Brönneke; Aleksandra Trifunovic; Giuseppe LoSasso; F Thomas Wunderlich; Jan-Wilhelm Kornfeld; Matthias Blüher; Martin Krönke; Jens C Brüning
Journal:  Cell Metab       Date:  2014-10-07       Impact factor: 27.287

9.  Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes.

Authors:  Joo-Won Park; Woo-Jae Park; Yael Kuperman; Sigalit Boura-Halfon; Yael Pewzner-Jung; Anthony H Futerman
Journal:  Hepatology       Date:  2012-12-06       Impact factor: 17.425

10.  Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length.

Authors:  Woo-Jae Park; Joo-Won Park; Alfred H Merrill; Judith Storch; Yael Pewzner-Jung; Anthony H Futerman
Journal:  Biochim Biophys Acta       Date:  2014-12
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  4 in total

Review 1.  The Lard Works in Mysterious Ways: Ceramides in Nutrition-Linked Chronic Disease.

Authors:  Rebekah J Nicholson; Marie K Norris; Annelise M Poss; William L Holland; Scott A Summers
Journal:  Annu Rev Nutr       Date:  2022-05-18       Impact factor: 9.323

2.  Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.

Authors:  Bhagirath Chaurasia; Trevor S Tippetts; Rafael Mayoral Monibas; Jinqi Liu; Ying Li; Liping Wang; Joseph L Wilkerson; C Rufus Sweeney; Renato Felipe Pereira; Doris Hissako Sumida; J Alan Maschek; James E Cox; Vincent Kaddai; Graeme Iain Lancaster; Monowarul Mobin Siddique; Annelise Poss; Mackenzie Pearson; Santhosh Satapati; Heather Zhou; David G McLaren; Stephen F Previs; Ying Chen; Ying Qian; Aleksandr Petrov; Margaret Wu; Xiaolan Shen; Jun Yao; Christian N Nunes; Andrew D Howard; Liangsu Wang; Mark D Erion; Jared Rutter; William L Holland; David E Kelley; Scott A Summers
Journal:  Science       Date:  2019-07-04       Impact factor: 47.728

Review 3.  Ceramides in Metabolism: Key Lipotoxic Players.

Authors:  Bhagirath Chaurasia; Scott A Summers
Journal:  Annu Rev Physiol       Date:  2020-11-06       Impact factor: 19.318

Review 4.  Metabolic Messengers: ceramides.

Authors:  Scott A Summers; Bhagirath Chaurasia; William L Holland
Journal:  Nat Metab       Date:  2019-10-24
  4 in total

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