Literature DB >> 29307517

Could Ceramides Become the New Cholesterol?

Scott A Summers1.   

Abstract

The Mayo Clinic recently introduced a diagnostic test that quantifies plasma ceramides in order to identify patients at risk of major adverse cardiac events. By comparing recent discoveries about these biomarker ceramides with the exhaustive body of literature surrounding cholesterol, Summers aims to highlight important advances and critically needed areas of investigation on this exciting class of bioactive lipids.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29307517     DOI: 10.1016/j.cmet.2017.12.003

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  60 in total

1.  Circulating Ceramide 16:0 in Heart Failure With Preserved Ejection Fraction.

Authors:  Ali Javaheri; Jeremy C Allegood; L Ashley Cowart; Julio A Chirinos
Journal:  J Am Coll Cardiol       Date:  2020-05-05       Impact factor: 24.094

2.  Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway.

Authors:  Nicholas B Blackburn; Laura F Michael; Peter J Meikle; Juan M Peralta; Marian Mosior; Scott McAhren; Hai H Bui; Melissa A Bellinger; Corey Giles; Satish Kumar; Ana C Leandro; Marcio Almeida; Jacquelyn M Weir; Michael C Mahaney; Thomas D Dyer; Laura Almasy; John L VandeBerg; Sarah Williams-Blangero; David C Glahn; Ravindranath Duggirala; Mark Kowala; John Blangero; Joanne E Curran
Journal:  J Lipid Res       Date:  2019-06-21       Impact factor: 5.922

3.  Suppressing the intestinal farnesoid X receptor/sphingomyelin phosphodiesterase 3 axis decreases atherosclerosis.

Authors:  Qing Wu; Lulu Sun; Xiaomin Hu; Xuemei Wang; Feng Xu; Bo Chen; Xianyi Liang; Jialin Xia; Pengcheng Wang; Daisuke Aibara; Shaofei Zhang; Guangyi Zeng; Chuyu Yun; Yu Yan; Yicheng Zhu; Michael Bustin; Shuyang Zhang; Frank J Gonzalez; Changtao Jiang
Journal:  J Clin Invest       Date:  2021-05-03       Impact factor: 14.808

4.  Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease.

Authors:  Annelise M Poss; J Alan Maschek; James E Cox; Benedikt J Hauner; Paul N Hopkins; Steven C Hunt; William L Holland; Scott A Summers; Mary C Playdon
Journal:  J Clin Invest       Date:  2020-03-02       Impact factor: 14.808

5.  Elevated serum ceramides are linked with obesity-associated gut dysbiosis and impaired glucose metabolism.

Authors:  Brandon D Kayser; Edi Prifti; Marie Lhomme; Eugeni Belda; Maria-Carlota Dao; Judith Aron-Wisnewsky; Anatol Kontush; Jean-Daniel Zucker; Salwa W Rizkalla; Isabelle Dugail; Karine Clément
Journal:  Metabolomics       Date:  2019-10-11       Impact factor: 4.290

6.  Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice.

Authors:  Pan Deng; Jessie B Hoffman; Michael C Petriello; Chun-Yan Wang; Xu-Sheng Li; Maria P Kraemer; Andrew J Morris; Bernhard Hennig
Journal:  J Lipid Res       Date:  2019-10-11       Impact factor: 5.922

7.  Does This Schlank Make Me Look Fat?

Authors:  Bhagirath Chaurasia; William L Holland; Scott A Summers
Journal:  Trends Endocrinol Metab       Date:  2018-04-21       Impact factor: 12.015

Review 8.  The role of hypoxia-inducible factors in metabolic diseases.

Authors:  Frank J Gonzalez; Cen Xie; Changtao Jiang
Journal:  Nat Rev Endocrinol       Date:  2018-12       Impact factor: 43.330

9.  Ceramide Biomarkers Predictive of Cardiovascular Disease Risk Increase in Healthy Older Adults After Bed Rest.

Authors:  Jonathan J Petrocelli; Alec I McKenzie; Ziad S Mahmassani; Paul T Reidy; Gregory J Stoddard; Annelise M Poss; William L Holland; Scott A Summers; Micah J Drummond
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2020-09-16       Impact factor: 6.053

10.  Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.

Authors:  Bhagirath Chaurasia; Trevor S Tippetts; Rafael Mayoral Monibas; Jinqi Liu; Ying Li; Liping Wang; Joseph L Wilkerson; C Rufus Sweeney; Renato Felipe Pereira; Doris Hissako Sumida; J Alan Maschek; James E Cox; Vincent Kaddai; Graeme Iain Lancaster; Monowarul Mobin Siddique; Annelise Poss; Mackenzie Pearson; Santhosh Satapati; Heather Zhou; David G McLaren; Stephen F Previs; Ying Chen; Ying Qian; Aleksandr Petrov; Margaret Wu; Xiaolan Shen; Jun Yao; Christian N Nunes; Andrew D Howard; Liangsu Wang; Mark D Erion; Jared Rutter; William L Holland; David E Kelley; Scott A Summers
Journal:  Science       Date:  2019-07-04       Impact factor: 47.728

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