Literature DB >> 29663143

Vertebral body osteonecrosis: proposal of a treatment-oriented classification system.

Matteo Formica1, Andrea Zanirato2, Luca Cavagnaro2, Marco Basso2, Stefano Divano2, Claudio Lamartina3, Pedro Berjano3, Lamberto Felli2, Carlo Formica3.   

Abstract

PURPOSE: To present a classification system for vertebral body osteonecrosis (VBON) based on imaging findings and sagittal alignment and consequently to propose treatment guidelines.
METHODS: Chart review and classification of imaging and clinical findings. An analysis of literature about VBON has been evaluated to conceive the classification. The current data allows to correlate radiological findings with different stages of the pathophysiological process and consequently to propose a patient-tailored treatment plan.
RESULTS: The classification identifies 4 stages: stage 0 (theoretical phase), stage 1 (early phase), stage 2 (instability phase) and stage 3 (fixed deformity phase). Local (angular kyphosis expressed as anterior-posterior wall height ratio) and global (sagittal vertical axis and pelvic tilt) sagittal alignment are considered as complementary modifiers to tailor the most suitable treatment. Stage 1 is generally managed conservatively. Stage 2 and 3 often require different surgical approaches according to local and global sagittal alignment.
CONCLUSIONS: The classification allows a systematic staging of this disease and can help establish a proper and patient-oriented treatment plan. Further researches are advocated to fully validate the proposed classification system. These slides can be retrieved under Electronic Supplementary Material.

Entities:  

Keywords:  Adult deformity; Classification; Sagittal alignment; Vertebral non-union; Vertebral osteonecrosis

Mesh:

Year:  2018        PMID: 29663143     DOI: 10.1007/s00586-018-5600-6

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  25 in total

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Review 2.  Pelvic parameters and global spine balance for spine degenerative disease: the importance of containing for the well being of content.

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Review 3.  Pathophysiology and natural history of avascular necrosis of bone.

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5.  Vertebral Bone Marrow Edema (VBME) in Conservatively Treated Acute Vertebral Compression Fractures (VCFs): Evolution and Clinical Correlations.

Authors:  Andrea Piazzolla; Giuseppe Solarino; Claudio Lamartina; Silvana De Giorgi; Davide Bizzoca; Pedro Berjano; Nunzia Garofalo; Stefania Setti; Franca Dicuonzo; Biagio Moretti
Journal:  Spine (Phila Pa 1976)       Date:  2015-07-15       Impact factor: 3.468

6.  Osteoanabolic therapy: a non-surgical option of treatment for Kümmell's disease?

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Review 7.  Kümmell's disease: a case report and literature review.

Authors:  Karin Swartz; Dominic Fee
Journal:  Spine (Phila Pa 1976)       Date:  2008-03-01       Impact factor: 3.468

8.  Corpectomy and expandable cage replacement versus third generation percutaneous augmentation system in case of vertebra plana: rationale and recommendations.

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Journal:  J Spine Surg       Date:  2017-09

9.  An Effective Treatment Option for Kümmell Disease With Neurological Deficits: Modified Transpedicular Subtraction and Disc Osteotomy Combined With Long-Segment Fixation.

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Journal:  Spine (Phila Pa 1976)       Date:  2016-08-01       Impact factor: 3.468

Review 10.  Posttraumatic Delayed Vertebral Collapse : Kummell's Disease.

Authors:  Jeongwook Lim; Seung-Won Choi; Jin-Young Youm; Hyon-Jo Kwon; Seon-Hwan Kim; Hyeon-Song Koh
Journal:  J Korean Neurosurg Soc       Date:  2017-12-29
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  3 in total

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Journal:  Int J Spine Surg       Date:  2021-09-22

Review 2.  What is the Current Evidence on Vertebral Body Osteonecrosis?: A Systematic Review of the Literature.

Authors:  Matteo Formica; Andrea Zanirato; Luca Cavagnaro; Marco Basso; Stefano Divano; Carlo Formica; Lamberto Felli
Journal:  Asian Spine J       Date:  2018-06-04

3.  Novel Surgical Strategy for Treating Osteoporotic Vertebral Fractures with Cord Compression.

Authors:  Dan-Qing Guo; Miao Yu; Shun-Cong Zhang; Yong-Chao Tang; Yun Tian; Da-Xing Li; Guo-Ye Mo; Yong-Xian Li; Hui-Zhi Guo; Pei-Jie Luo; Teng-Peng Zhou; Yan-Huai Ma; Yusupov Abdukodir; Pan-Jie Liu
Journal:  Orthop Surg       Date:  2019-11-21       Impact factor: 2.071

  3 in total

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