| Literature DB >> 29659692 |
Tair Ben-Porat1,2, Ram Elazary3, Shiri Sherf-Dagan4, Ariela Goldenshluger1, Ronit Brodie3, Yoav Mintz3, Ram Weiss2.
Abstract
Bariatric surgery (BS) is an effective treatment for morbid obesity and its associated comorbidities. Following such a procedure, however, patients are at risk of developing metabolic bone disease owing to the combination of rapid weight loss, severely restricted dietary intake, and reduced intestinal nutrient absorption. Patients undergoing malabsorptive procedures are at a higher risk of postoperative bone health deterioration than those undergoing restrictive procedures; however, studies have demonstrated negative skeletal consequences of restrictive procedures as well. The clinical practice guidelines of some international associations have previously addressed preoperative evaluation and postoperative clinical care in order to maintain bone health in BS patients. Nevertheless, some issues regarding bone health in BS patients remain unclear owing to the lack of relevant randomized clinical trials, including doses of nutritional supplements pre- and post-BS. This review summarizes the current data regarding the skeletal consequences of BS and its mechanisms, with an emphasis on the preventive strategies and nutritional care that may be warranted in order to attenuate bone deterioration following BS.Entities:
Mesh:
Year: 2018 PMID: 29659692 PMCID: PMC5916426 DOI: 10.1093/advances/nmx024
Source DB: PubMed Journal: Adv Nutr ISSN: 2161-8313 Impact factor: 8.701