Literature DB >> 23303909

Gastric acid, calcium absorption, and their impact on bone health.

Sascha Kopic1, John P Geibel.   

Abstract

Calcium balance is essential for a multitude of physiological processes, ranging from cell signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a major factor for maintaining systemic calcium homeostasis. Recent observations indicate that a reduction of gastric acidity may impair effective calcium uptake through the intestine. This article reviews the physiology of gastric acid secretion, intestinal calcium absorption, and their respective neuroendocrine regulation and explores the physiological basis of a potential link between these individual systems.

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Year:  2013        PMID： 23303909     DOI： 10.1152/physrev.00015.2012

Source DB:  PubMed          Journal:  Physiol Rev        ISSN： 0031-9333            Impact factor:   37.312


  44 in total

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