Literature DB >> 2965812

Purification and functional characterization of a cellular transcription factor that binds to an enhancer element within the adenovirus early EIIa promoter.

P Jalinot1, M Wintzerith, M Gaire, C Hauss, J M Egly, C Kédinger.   

Abstract

The adenovirus EIa-inducible early EIIa (EIIaE) promoter is comprised of several sequence elements essential for constitutive and induced expression. We report here the purification of the host-cell factor that interacts with the major upstream element of this promoter, extending between positions -90 and -70 with respect to the main EIIaE cap site and exhibiting enhancer properties. The purified factor, which corresponds to a 40- to 43-kDa polypeptide, specifically binds to its recognition site and stimulates EIIaE promoter activity when added to an in vitro transcription system, reconstituted from purified factors and RNA polymerase. The implication of this factor in the control of the other adenovirus early genes is discussed.

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Year:  1988        PMID： 2965812      PMCID： PMC280021          DOI： 10.1073/pnas.85.8.2484

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  33 in total

1.  Identical genomic footprints of the adenovirus EIIa promoter are detected before and after EIa induction.

Authors:  B Devaux; G Albrecht; C Kedinger
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

2.  An adenovirus type 5 early gene function regulates expression of other early viral genes.

Authors:  N Jones; T Shenk
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

4.  Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis.

Authors:  M Fried; D M Crothers
Journal:  Nucleic Acids Res       Date:  1981-12-11       Impact factor: 16.971

5.  Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes.

Authors:  D A Hager; R R Burgess
Journal:  Anal Biochem       Date:  1980-11-15       Impact factor: 3.365

6.  The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element.

Authors:  P Hearing; T Shenk
Journal:  Cell       Date:  1983-07       Impact factor: 41.582

7.  DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

Authors:  J L Manley; A Fire; A Cano; P A Sharp; M L Gefter
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

8.  Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs.

Authors:  A J Berk; F Lee; T Harrison; J Williams; P A Sharp
Journal:  Cell       Date:  1979-08       Impact factor: 41.582

9.  Specific in vitro initiation of transcription on the adenovirus type 2 early and late EII transcription units.

Authors:  D J Mathis; R Elkaim; C Kédinger; P Sassone-Corsi; P Chambon
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

10.  The adenovirus-2 EIIa early gene promoter: sequences required for efficient in vitro and in vivo transcription.

Authors:  R Elkaim; C Goding; C Kédinger
Journal:  Nucleic Acids Res       Date:  1983-10-25       Impact factor: 16.971
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  19 in total

1.  Isolation and characterization of two novel, closely related ATF cDNA clones from HeLa cells.

Authors:  M Gaire; B Chatton; C Kedinger
Journal:  Nucleic Acids Res       Date:  1990-06-25       Impact factor: 16.971

2.  Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

Authors:  T Hai; T Curran
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-01       Impact factor: 11.205

3.  Different biological activities of the hetero- and homodimers formed by the 47- and 43-kilodalton proteins of transcription factor ATF/E4TF3.

Authors:  T Wada; H Watanabe; Y Usuda; H Handa
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

4.  Two distinct cellular proteins interact with the EIa-responsive element of an adenovirus early promoter.

Authors:  P Jansen-Durr; M Wintzerith; B Reimund; C Hauss; C Kédinger
Journal:  J Virol       Date:  1990-05       Impact factor: 5.103

5.  The adenovirus EII early promoter has multiple EIA-sensitive elements, two of which function cooperatively in basal and virus-induced transcription.

Authors:  C F Manohar; J Kratochvil; B Thimmapaya
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

6.  A GC-box motif upstream of the B19 parvovirus unique promoter is important for in vitro transcription.

Authors:  M C Blundell; C R Astell
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

7.  Identification of transcription factories in nuclei of HeLa cells transiently expressing the Us11 gene of herpes simplex virus type 1.

Authors:  F Puvion-Dutilleul; S Besse; J J Diaz; K Kindbeiter; M Vigneron; S L Warren; C Kedinger; J J Madjar; E Puvion
Journal:  Gene Expr       Date:  1997

8.  Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter.

Authors:  L A Berkowitz; K T Riabowol; M Z Gilman
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

9.  Different binding specificities and transactivation of variant CRE's by CREB complexes.

Authors:  D M Benbrook; N C Jones
Journal:  Nucleic Acids Res       Date:  1994-04-25       Impact factor: 16.971

10.  Identification and functional characterisation of the cellular activating transcription factor 43 (ATF-43) protein.

Authors:  H C Hurst; N F Totty; N C Jones
Journal:  Nucleic Acids Res       Date:  1991-09-11       Impact factor: 16.971
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