Literature DB >> 291030

An adenovirus type 5 early gene function regulates expression of other early viral genes.

N Jones, T Shenk.   

Abstract

We have identified an adenovirus type 5(Ad5) early gene function located in early region 1 which is required for the production of early cytoplasmic mRNAs corresponding to early regions 2, 3, and 4. Mutant dl312 (lacks the segment between 1.5 and 4.5 map units) grows as well as wild-type virus in 293 cells (Ad5-transformed human embryonic kidney cells), but its growth is severely restricted in HeLa cells. We detect no viral RNAs in the cytoplasm of dl312-infected HeLa cells. Viral RNA sequences are present, however, in dl312-infected HeLa cell nuclei.

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Year:  1979        PMID： 291030      PMCID： PMC383893          DOI： 10.1073/pnas.76.8.3665

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  24 in total

1.  Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide.

Authors:  J Casey; N Davidson
Journal:  Nucleic Acids Res       Date:  1977       Impact factor: 16.971

2.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

3.  The initiation sites for RNA transcription in Ad2 DNA.

Authors:  R M Evans; N Fraser; E Ziff; J Weber; M Wilson; J E Darnell
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

4.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

5.  Early Ad-2 transcription units: only promoter-proximal RNA continues to be made in the presence of DRB.

Authors:  P B Sehgal; N W Fraser; J E Darnell
Journal:  Virology       Date:  1979-04-15       Impact factor: 3.616

6.  Mapping of RNA initiation sites by high doses of uv irradiation: evidence for three independent promoters within the left 11% of the Ad-2 genome.

Authors:  M C Wilson; N W Fraser; J E Darnell
Journal:  Virology       Date:  1979-04-15       Impact factor: 3.616

7.  Isolation of deletion and substitution mutants of adenovirus type 5.

Authors:  N Jones; T Shenk
Journal:  Cell       Date:  1978-01       Impact factor: 41.582

8.  Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome.

Authors:  D J Spector; M McGrogan; H J Raskas
Journal:  J Mol Biol       Date:  1978-12-15       Impact factor: 5.469

9.  Effect of protein synthesis inhibitors on viral mRNA's synthesized early in adenovirus type 2 infection.

Authors:  F Eggerding; H J Raskas
Journal:  J Virol       Date:  1978-01       Impact factor: 5.103

10.  Structure of the adenovirus 2 early mRNAs.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1978-07       Impact factor: 41.582
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  358 in total

1.  Bak and Bax function to limit adenovirus replication through apoptosis induction.

Authors:  Andrea Cuconati; Kurt Degenhardt; Ramya Sundararajan; Alan Anschel; Eileen White
Journal:  J Virol       Date:  2002-05       Impact factor: 5.103

2.  Control of adenovirus early gene expression: posttranscriptional control mediated by both viral and cellular gene products.

Authors:  M G Katze; H Persson; L Philipson
Journal:  Mol Cell Biol       Date:  1981-09       Impact factor: 4.272

3.  Adenovirus infection of differentiated F9 cells results in a global shut-off of differentiation-induced gene expression.

Authors:  R J Weigel; J R Nevins
Journal:  Nucleic Acids Res       Date:  1990-10-25       Impact factor: 16.971

4.  Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence.

Authors:  K T Jeang; I Boros; J Brady; M Radonovich; G Khoury
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

5.  Phosphorylation in vitro of Escherichia coli-produced 235R and 266R tumor antigens encoded by human adenovirus type 12 early transformation region 1A.

Authors:  L A Lucher; P M Loewenstein; M Green
Journal:  J Virol       Date:  1985-10       Impact factor: 5.103

6.  Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression.

Authors:  B E Roberts; J S Miller; D Kimelman; C L Cepko; I R Lemischka; R C Mulligan
Journal:  J Virol       Date:  1985-11       Impact factor: 5.103

7.  Synthesis in Escherichia coli of human adenovirus type 12 transforming proteins encoded by early region 1A 13S mRNA and 12S mRNA.

Authors:  D Kimelman; L A Lucher; K H Brackmann; J S Symington; M Ptashne; M Green
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

8.  Identification of adenovirus 12-encoded E1A tumor antigens synthesized in infected and transformed mammalian cells and in Escherichia coli.

Authors:  L A Lucher; D Kimelman; J S Symington; K H Brackmann; M A Cartas; H Thornton; M Green
Journal:  J Virol       Date:  1984-10       Impact factor: 5.103

9.  Activation of RNA polymerase III transcription of human Alu repetitive elements by adenovirus type 5: requirement for the E1b 58-kilodalton protein and the products of E4 open reading frames 3 and 6.

Authors:  B Panning; J R Smiley
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272

10.  Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters.

Authors:  H K Wong; E B Ziff
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103
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