| Literature DB >> 2963956 |
B Devaux1, G Albrecht, C Kedinger.
Abstract
Genomic DNase I footprinting was used to compare specific protein binding to the adenovirus type 5 early, EIa-inducible, EIIa promoter. Identical protection patterns of the promoter region were observed whether EIIa transcription was undetectable or fully induced. These results suggest that EIa-mediated transcriptional induction does not increase binding of limiting transcription factors to the promoter but rather that transactivation results from the proper interactions between factors already bound to their cognate sequences.Entities:
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Year: 1987 PMID: 2963956 PMCID: PMC368143 DOI: 10.1128/mcb.7.12.4560-4563.1987
Source DB: PubMed Journal: Mol Cell Biol ISSN: 0270-7306 Impact factor: 4.272